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Electric brain boost: new trial tests if zapping the scalp can fix Word-Finding problems after TBI

NCT ID NCT06848140

Symptom relief Sponsor: Beth Israel Deaconess Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a technique called high-definition transcranial direct current stimulation (HD-tDCS) can improve word-finding difficulties in people who had a traumatic brain injury at least a year ago. The device delivers a very low electrical current through electrodes on the scalp to target brain areas involved in memory and language. Researchers will compare active stimulation to a sham (fake) version in 24 adults to see if it helps them recall words more easily.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high definition transcranial direct current stimulation (HD-tDCS)
What this could lead to
If it works, this could point toward a non-invasive, drug-free way to improve word-finding and memory in people with long-term traumatic brain injury.
What could go wrong
This is a small, early-phase study with only 24 participants. The effect may be small or not last, and individual results can vary. Brain stimulation can cause mild tingling or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 85 * Fluent in speaking and reading English * Able to provide informed consent * Has a TBI at least one year prior to enrollment and not related to military experience * Has a confirmation of verbal retrieval difficulties as measured by the Verbal Retrieval Difficulty Interview questions Exclusion Criteria: * Lifetime major or active neurologic conditions (e.g., stroke, epilepsy, brain tumor, dementia, seizure occurrence less than one year ago) * Lifetime major or active cardiovascular conditions (e.g., cardiac arrythmia, heart failure, heart attack) * Current substance use disorder * Lifetime major psychiatric disorders (e.g., schizophrenia, bipolar disorder) * Severe depression at the time of enrollment (BDI-II \>= 29) or psychiatric ER visits or hospitalization less than 6 months ago prior to enrollment * Current sensory (e.g., blind, deaf) or physical (e.g., severe motor weakness) impairment that interferes with testing * Contraindications for tDCS or MRI * The person cannot be left alone for 8+ hours. * Not verbally communicative. * Currently undergoing and not wishing to discontinue speech and cognitive therapy during study participation. * Incapable of understanding the consent or unable to consent for oneself. * Unable to travel to BIDMC's Berenson-Allen Center * Pregnancy

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic brain injury cognitive disorder dementia pugilistica Neurobehavioral Manifestations nominal aphasia traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acquired brain injury Cognitive change Cognitive symptom Traumatic brain injury Word finding difficulty

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.