Statins after brain bleed: to stop or not to stop?
NCT ID NCT03936361
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 27 times
Summary
This Phase 3 trial is testing whether people who were taking statins before a brain hemorrhage should continue or stop them afterward. Researchers will also check if a person's APOE gene affects the risk. The study plans to enroll 1,456 participants aged 50 and older who had a spontaneous lobar brain bleed. The goal is to find the safest strategy to prevent another hemorrhage or other serious heart and brain events.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Statins (cholesterol-lowering drugs)
What this could lead to
If successful, this trial could provide clear guidance on whether to continue or stop statins after a brain hemorrhage, potentially reducing the risk of another bleed or stroke.
What could go wrong
This is a large Phase 3 trial, but results may not apply to all patients. The study focuses on a specific type of brain hemorrhage, and the decision may still depend on individual health factors.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.