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Immunotherapy combo shows promise for Hard-to-Treat breast cancer

NCT ID NCT03095352

First seen Jan 08, 2026 · Last updated May 23, 2026 · Updated 22 times

Summary

This study tested whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (carboplatin) helps control breast cancer that has returned on the chest wall. The trial included 76 women with either triple-negative or hormone-resistant breast cancer. Researchers measured how many patients had their disease shrink or stay stable after 18 weeks of treatment.

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Contacts and locations

Locations

  • Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Indiana University/Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

  • University of Pittsburgh Cancer Institute

    Pittsburgh, Pennsylvania, 15232, United States

  • Vanderbilt University/Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.