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Radiation and immune drugs join forces against tough cancers

NCT ID NCT02639026

First seen Jan 05, 2026 · Last updated May 19, 2026 · Updated 22 times

Summary

This early-phase trial tested whether combining a special type of radiation (hypofractionated radiotherapy) with two immunotherapy drugs (MEDI4736 and tremelimumab) is safe and tolerable for people with advanced melanoma, lung, breast, or pancreatic cancer that has spread. The study included 53 participants and focused on tracking side effects. The goal was to find the best way to combine these treatments to potentially help the immune system fight cancer more effectively.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

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