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Ice plant cream may shield cancer patients from chemo side effect

NCT ID NCT05755646

Prevention Sponsor: University Hospital Tuebingen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study tested whether an ice plant cream could prevent hand-foot syndrome (pain, redness, peeling on hands and feet) in 15 breast cancer patients receiving doxorubicin or docetaxel chemotherapy. The main goal was to see if a larger study is possible, not to prove the cream works. Results will help design future research.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

15 people

The number who actually took part.

Started

Mar 2023

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Breast cancer patients * Therapy with Doxorubicin and/or Docetaxel * Karnofsky performance status scale \> 80 * Informed consent Exclusion Criteria: * Patients with previous skin disease and/or polyneuropathy * Intolerance or allergic reaction on at least one ingredient of Ice Plant Intensive Cream * Already receiving chemotherapy * Usage of Ice Plant Intensive Cream before trial * Severe physical or psychological illness due to which the patient is not able to participate in the study * Lack of German language skills

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hand-foot syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Hand-foot syndrome

Contacts and locations

Locations

  • Robert-Bosch-Hospital

    Stuttgart, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.