Can MRI better spot early breast cancer spread?
NCT ID NCT00874458
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether MRI can more accurately measure the size of ductal carcinoma in situ (a very early form of breast cancer) compared to standard mammography. Forty women with the condition had MRI scans before surgery. Researchers then compared the MRI results with the actual tumor size found during surgery to see how well MRI predicts the extent of disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- magnetic resonance imaging (MRI)
- What this could lead to
- If successful, MRI could become a standard tool to more accurately assess how far ductal carcinoma in situ has spread before surgery.
- What could go wrong
- This is a small, completed study with only 40 participants, so results may not apply to all patients. MRI may not always match surgical findings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Start date
-
Apr 2007
- Finished
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Dec 2013
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 120 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
DISEASE CHARACTERISTICS: * Diagnosis of ductal breast carcinoma in situ * Any grade disease allowed * Unifocal disease by mammography * No history of breast cancer * Hormone receptor status not specified PATIENT CHARACTERISTICS: * Menopausal status not specified * WHO performance status 0-2 * Glomerular filtration rate ≥ 30 mL/min * Not pregnant or nursing * Fertile patients must use effective contraception * No allergy or contraindication to contrast MRI * No pacemaker or vascular clip PRIOR CONCURRENT THERAPY: * No prior or concurrent liver transplantation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre Antoine Lacassagne
Nice, 06189, France
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