Centre Antoine Lacassagne

This study tests whether adding a focused radiation boost (CyberKnife) after standard chemotherapy and radiation can help people with locally advanced non-small cell lung cancer live longer without the disease getting worse. About 42 adults with stage III lung cancer that cannot …

This early-phase trial is testing whether adding acetazolamide (a drug that blocks carbonic anhydrase) to standard chemotherapy and radiation or immunotherapy can help treat small cell lung cancer. About 27 adults with either localized or extensive small cell lung cancer will tak…

This study tests whether using a frozen glove plus a tight surgical glove on one hand works better than a frozen glove alone to prevent nerve damage from paclitaxel chemotherapy in breast cancer patients. About 60 women with early-stage breast cancer will each serve as their own …

This study is for women aged 65 and older with early-stage breast cancer. It tests giving a single dose of radiation during surgery instead of weeks of daily radiation afterward. The goal is to see if this approach is safe and causes fewer side effects. About 40 participants will…

This study aims to find unique chemical patterns (metabolomic signatures) in the blood, urine, and tumor tissue of people with upper aerodigestive tract cancers, such as mouth and throat cancers. Researchers will analyze samples from 250 patients at diagnosis and after treatment …

This study takes tumor samples from 50 patients with specific genetic mutations to grow 3D cell clusters called spheroids in the lab. Researchers will then test various cancer drugs on these spheroids to see which treatments work best for that mutation. The goal is to create a to…