Centre Antoine Lacassagne

This early-phase trial is testing whether adding acetazolamide (a drug that blocks carbonic anhydrase) to standard chemotherapy and radiation or immunotherapy can help treat small cell lung cancer. About 27 adults with either localized or extensive small cell lung cancer will tak…

This study tests whether adding a very precise, high-dose radiation boost (CyberKnife) after standard chemotherapy and radiation can help people with locally advanced non-small cell lung cancer live longer without the cancer growing. About 42 adults with stage III lung cancer tha…

This study looks at whether using a frozen glove plus a tight surgical glove can prevent nerve damage (numbness, pain, tingling) caused by the chemotherapy drug paclitaxel in breast cancer patients. About 60 women with early-stage breast cancer will wear a frozen glove on one han…

This study is testing a new way to give radiation therapy during breast cancer surgery for women aged 65 and older with early-stage cancer. The goal is to see if this approach is safe and causes fewer side effects. About 40 participants will receive the treatment and be monitored…

This study aims to find unique chemical patterns (metabolomic signatures) in blood, urine, and tumor samples from 250 people with head and neck cancer. By analyzing these patterns, researchers hope to enable earlier diagnosis, better treatment decisions, and quicker detection of …

This study takes small pieces of tumors from 50 patients who have certain genetic changes (mutations) and grows them in the lab as 3D cell clusters called spheroids. Researchers will then test different cancer drugs on these spheroids to see which ones work best. The goal is to c…