Centre Antoine Lacassagne

This study tests whether a special type of internal radiation (contact X-ray brachytherapy) can help more people with early rectal cancer keep their rectum compared to standard external radiation. About 148 adults with small, early-stage tumors will receive standard chemoradiatio…

This study is testing a combination of two drugs, gemtuzumab ozogamicin (GO) and gilteritinib, in adults with a type of acute myeloid leukemia (AML) that has come back or not responded to treatment. The leukemia must have a specific genetic change called FLT3 mutation. The goal i…

This study tests a combination of two drugs, pazopanib and temozolomide, for people with a newly diagnosed aggressive brain cancer called glioblastoma. The goal is to find the safest dose of pazopanib to add to standard treatment after surgery and radiation. About 51 adults aged …

This study aimed to test the safety and effectiveness of adding the drug ribociclib to standard hormone therapy and radiation for women aged 70 and older with a certain type of breast cancer. The goal was to control the disease without surgery. However, the trial was withdrawn be…

This study compares two imaging methods to see how well brain blood vessels respond to a drug called acetazolamide. The standard method uses scintigraphy, while the newer method uses a PET scan. Researchers want to know if the PET scan is just as good. The study involves 19 adult…