New combo aims to tame harsh side effects of advanced breast cancer treatment
NCT ID NCT05520723
First seen Jan 04, 2026 · Last updated May 20, 2026 · Updated 26 times
Summary
This study tested whether adding two supportive drugs (loperamide for diarrhea and G-CSF for low white blood cells) could reduce severe side effects of the cancer drug sacituzumab govitecan. It involved 50 adults with advanced triple-negative or luminal breast cancer that had spread and was no longer curable with surgery. The main goal was to see if the combo lowered rates of serious diarrhea and neutropenia during the first two treatment cycles.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hospital Arnau de Vilanova
Lleida, Lleida, Spain
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Hospital Quiron San Camilo- Ruber Juan Bravo
Madrid, Madrid, 28006, Spain
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Hospital Quirón Valencia
Valencia, Valencia, Spain
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Hospital Ramón y Cajal
Madrid, Spain
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Hospital Universitario A Coruña
A Coruña, A Coruna, Spain
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Hospital Universitario Clínico San Cecilio de Granada
Granada, Spain
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Hospital Universitario Donostia
San Sebastián, Donostia, 20014, Spain
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Hospital Universitario General de Catalunya
Sant Cugat del Vallès, Barcelona, 08190, Spain
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Hospital Universitario Virgen del Rocio
Seville, Spain
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Hospital de Sant Joan Despí - Moises Broggi
Barcelona, Spain
Conditions
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