Advanced HR+/HER2- breast cancer
Clinical trials for Advanced HR+/HER2- breast cancer explained in plain language.
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New drug IEV407 takes on advanced breast cancer in early trial
Disease control Recruiting nowThis early-phase study tests a new drug called IEV407, alone or with hormone therapy, in people with advanced HR+/HER2- breast cancer that has stopped responding to standard treatments. The main goals are to check safety and find the right dose. About 194 participants will take p…
Matched conditions: ADVANCED HR+/HER2- BREAST CANCER
Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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New combo therapy aims to control advanced breast cancer
Disease control Recruiting nowThis study tests a new drug called ECI830, alone or with other cancer drugs (ribociclib and fulvestrant), in people with advanced hormone receptor-positive, HER2-negative breast cancer or certain solid tumors. The goal is to find safe doses and see if the combination can slow can…
Matched conditions: ADVANCED HR+/HER2- BREAST CANCER
Phase 1/2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New drug combo shows promise for Hard-to-Treat breast cancer
Disease control Recruiting nowThis study tests a new drug called GVV858, alone or with hormone therapy, in people with advanced hormone receptor-positive, HER2-negative breast cancer and other solid tumors. The goal is to find the safest dose and see how well it works. About 205 adults whose cancer has progre…
Matched conditions: ADVANCED HR+/HER2- BREAST CANCER
Phase 1/2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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Blood test timing could unlock secrets of advanced breast cancer
Knowledge-focused Recruiting nowThis study looks at how the timing of a blood test that detects tumor DNA (ctDNA) affects understanding of prognosis and treatment choices in people with advanced HR+/HER2- breast cancer. Researchers will follow 400 participants to see how ctDNA levels and gene mutations relate t…
Matched conditions: ADVANCED HR+/HER2- BREAST CANCER
Sponsor: Geneplus-Beijing Co. Ltd. • Aim: Knowledge-focused
Last updated Sep 17, 2026 00:00 UTC