Blood test timing could unlock secrets of advanced breast cancer
NCT ID NCT07681323
First seen Jul 02, 2026 · Last updated Sep 16, 2026 · Updated 7 times
Summary
This study looks at how the timing of a blood test that detects tumor DNA (ctDNA) affects understanding of prognosis and treatment choices in people with advanced HR+/HER2- breast cancer. Researchers will follow 400 participants to see how ctDNA levels and gene mutations relate to survival and treatment response. The goal is to learn whether earlier or later testing provides better information for guiding care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better predict outcomes and tailor treatments for advanced breast cancer patients.
- What could go wrong
- This is an observational study, so it does not test a new treatment. Results may not change practice without further trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with histologically confirmed advanced breast cancer.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Histologically confirmed advanced breast cancer * Age ≥18 years * Expected survival \>3 months * Willing to undergo ctDNA testing and sign informed consent form Exclusion Criteria: * The subject has not signed the informed consent form. * Pregnant or breastfeeding women. * Other situations deemed by the investigator as unsuitable for inclusion in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cancer Institute and Hospital, Chinese Academy of Medical Sciences
RECRUITINGBeijing, 100100, China
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