Ain Shams University

This study compared two surgical techniques for removing large kidney stones stuck in the upper ureter. One hundred adult patients were randomly assigned to have their stones broken up using either an 'antegrade' (through the kidney) or 'retrograde' (through the bladder) approach…

This study tested two different ways to place a collagen membrane during immediate dental implant placement. Twenty patients with a badly decayed tooth in a visible area received an implant with bone graft and a membrane placed either inside or outside the socket. Researchers mea…

This completed Phase 3 trial tested whether trimetazidine, a medication typically used for chest pain, could help people recover from an ischemic stroke (caused by a blocked blood vessel in the brain). The study involved 60 adults who had recently suffered a stroke, and it aimed …

This study tested whether giving a special, easy-to-digest protein drink soon after surgery helps critically ill mothers who had a C-section. Researchers compared mothers who received the drink within hours of surgery to those who followed the standard protocol of waiting for nor…

This study tested whether giving oral vitamin C to patients with kidney failure on regular dialysis could safely help control their anemia. It involved 60 patients to see if the vitamin could reduce the amount of a standard anemia medication (erythropoietin) they needed. The goal…

This study tested whether adding a daily probiotic supplement to standard lupus medication could help better control the disease. For 12 weeks, half of the 40 adult participants with active lupus took the probiotic alongside their usual treatment, while the other half continued w…

This study compared two medical devices used during kidney stone surgery. Researchers tested whether a newer suction sheath helps remove stone fragments better than the traditional sheath. 140 adults with single kidney stones up to 20mm were randomly assigned to receive surgery w…

This study tested whether giving clot-busting drugs (thrombolysis) to patients with severe lung clots (pulmonary embolism) could reduce deaths within 30 days. Researchers compared the drugs against standard blood thinners in 100 patients who were at high risk but had low risk of …

This study tested whether the type of fluid used to rinse the bladder after tumor removal surgery affects whether the cancer comes back. Researchers compared three different rinse solutions in 150 patients with early-stage bladder cancer. The goal was to see which solution was be…

This study tested whether pentoxifylline, a medication typically used for circulation problems, could reduce inflammation and slow kidney disease progression in non-diabetic patients. Researchers enrolled 42 adults with moderate to severe chronic kidney disease but without diabet…

This study compared two different ways to drain urine after surgery to correct a common birth defect in boys called hypospadias. It involved 86 boys with a mild form of the condition to see which drainage method and how long it was used led to fewer problems, like urine leaks, af…

This study aimed to find the better surgery for Superior Mesenteric Artery Syndrome (SMAS), a rare condition where a major blood vessel pinches the small intestine, causing severe nausea, vomiting, and weight loss. Researchers randomly assigned 20 patients to receive one of two s…

This study tested whether adding a Coenzyme Q10 supplement to standard treatment could help control lupus disease activity in children. Researchers enrolled 60 children aged 6-16 with moderate to severe lupus and followed them for three months. They compared those taking the supp…

This small study tested whether teaching life skills like problem-solving, communication, and stress management could help men with substance use disorders feel more confident in their ability to stay sober. Researchers worked with 45 men in a Cairo hospital who had relapsed befo…

This study tested whether a custom-made temporary hip implant could effectively control infection while maintaining reasonable function during a two-stage replacement procedure for infected hip joints. Researchers followed 25 patients who received this custom spacer after removal…

This study compared two common methods of non-invasive breathing support for young children (aged 1 month to 5 years) who were in the pediatric intensive care unit with severe breathing problems from pneumonia or bronchiolitis. Researchers wanted to see which method—High-Velocity…

This study tested whether adding two medications, Cerebrolysin and Amantadine sulfate, to standard ICU care could help people recover better from a serious traumatic brain injury (TBI). It involved 150 adults with moderate to severe TBI. Researchers measured changes in consciousn…

This study compared two types of weight-loss surgery to see which one is better at helping people with severe obesity and type 2 diabetes. It involved 40 patients who received either a newer or a more established procedure. Researchers measured changes in gut hormones and blood s…

This study compared two ways of positioning patients during surgery for a serious type of hip fracture. Researchers wanted to see if lying on one's side (lateral decubitus) or lying on one's back on a special table (supine on traction table) led to better bone alignment, less rad…

This study compared two procedures for removing dense kidney stones in children aged 2 to 12. One hundred kids were randomly assigned to receive either a minimally invasive surgery (mini-PNL) or a non-surgical shockwave treatment (SWL). The main goal was to see which method was b…

This study compared two different settings on breathing machines for patients with severe Acute Respiratory Distress Syndrome (ARDS), a life-threatening lung condition. It involved 90 adult patients on ventilators to see if a newer method (APRV) was better than a standard one (PR…

This study tested if a diabetes medication called Empagliflozin could help improve the structure and pumping ability of the heart in people with diabetes who had a serious heart attack. It involved 200 participants who received one of two doses of the drug and were monitored for …

This study compared three different injection treatments for shrinking low-flow vascular malformations, which are abnormal tangles of blood vessels. 75 patients received one of three medications (ethanol, bleomycin, or polidocanol) injected directly into the malformation. Researc…

This study compared two different weight loss surgeries to see which one works better for people with severe obesity. Researchers followed 80 patients to measure weight loss results, health improvements, quality of life changes, and any complications. They compared a newer proced…

This study tested a new, less invasive laser procedure against the standard surgery for treating an enlarged prostate (BPH). It involved 56 men and aimed to see if the laser method was as effective at relieving symptoms while being safer and allowing for a quicker recovery. Resea…

This study compared two different settings on breathing machines to see which one works better at helping patients breathe on their own after a serious lung problem. Doctors tested 50 adults with respiratory failure who were ready to try breathing without full machine support. Th…

This study tested a specific 3D-shaped titanium plate for surgically fixing broken jawbones near the joint. Fourteen adult patients with this type of fracture had the plate implanted. Doctors used CT scans to check how well the bone healed and measured patients' pain levels and j…

This study tested whether a newer type of diabetes drug (a GLP-1 receptor agonist) works better than standard insulin therapy for children and teenagers with transfusion-dependent thalassemia who also have diabetes. The trial involved 80 participants aged 10-18 and compared how w…

This study aimed to see if two antioxidant supplements, N-Acetylcysteine or Alpha-Lipoic Acid, could prevent or reduce kidney damage in critically ill patients who needed the powerful antibiotic colistin. Colistin is a last-resort treatment for dangerous, drug-resistant infection…

This completed study compared three different surgical techniques for removing kidney stones up to 2 centimeters in size. Ninety adults with single kidney stones had one of three minimally invasive procedures using different tools to reach and break up the stone. Researchers want…

This study compared two surgical methods for removing medium-sized bladder tumors (2-6 cm) to see which provides better tissue samples for diagnosis. Researchers tested whether removing the tumor in one piece (en-bloc) gives clearer information about cancer depth compared to the …

This study compared two different anesthesia combinations used during major spine surgery. The goal was to see which method better preserves the electrical signals doctors use to monitor nerve and spinal cord function during the operation, helping to prevent nerve damage. It invo…

This study compared two different ways to create the small tunnel needed for kidney stone removal surgery. Researchers wanted to see if a 'one-shot' method was as safe and effective as the traditional 'serial' method for creating this access point. The study involved 60 adult pat…

This study tested if rinsing the surgical area with warm saline (body temperature) instead of room-temperature saline reduces early bleeding after a common weight loss surgery. Involving 200 patients, it found this simple, low-cost change during surgery helped control bleeding be…

This study tested if giving the drug atropine during an emergency heart attack procedure could prevent dangerous heart rhythm problems and low blood pressure. It involved 158 people having a specific type of heart attack (inferior STEMI) who were undergoing a procedure to open a …

This study tested if giving patients a water pill (furosemide) during a common kidney stone removal surgery helps wash out more stone fragments. Researchers compared 2000 adults who got the pill during surgery to those who got standard care. They checked a month later with a CT s…

This study aimed to see if a type of diabetes medication (SGLT2 inhibitors) could help protect kidney function in people with chronic kidney disease, whether they had diabetes or not. Researchers compared changes in a key measure of kidney health (eGFR) in 60 adult participants w…

This study compared two different surgical methods for removing dense kidney stones in children aged 6 to 12. Researchers tested whether a procedure called mini PCNL or a procedure called FURS was better at completely removing the stones. They measured which surgery had fewer com…

This study compared two surgical techniques to heal a broken scaphoid bone in the wrist that failed to mend on its own. Researchers tested a newer, less invasive 'keyhole' (arthroscopic) method against the traditional open surgery to see which leads to better bone healing, faster…

This study tested whether natural gels made from curcumin (the compound in turmeric) work as well as standard antibiotic or calcium hydroxide pastes to heal jawbone infections around teeth that need a second root canal treatment. Researchers compared four different medications pl…

This study tested whether a digital therapy app called MITA could help improve language skills in children with autism. Researchers enrolled 150 children aged 2 to 8 to use the app, which was designed to target specific thinking challenges common in autism. The main goal was to s…

This study compared three different heart-strengthening drugs (Levosimendan, Dobutamine, and Milrinone) in patients hospitalized with sudden worsening of heart failure who also had reduced kidney function. It aimed to see which drug was most effective at improving both heart and …

This study tested whether vitamin D supplements work as well as a common bedwetting medicine (desmopressin) for children who wet the bed at night and have low vitamin D levels. Researchers compared three approaches over six months: vitamin D alone, the medicine alone, or both tog…

This study tested two different tooth-colored filling materials to repair weak enamel on permanent front teeth in children. Doctors used a special injection technique to apply either a giomer or a composite resin filling. They followed 14 children for two years to see which mater…

This study tested whether resveratrol, a natural compound found in foods like grapes and peanuts, could help control kidney damage in young people with long-term type 1 diabetes. For six months, 60 teenagers with early signs of diabetic kidney disease either took resveratrol pill…

This study tested whether adding a medication called cilostazol to standard rheumatoid arthritis (RA) treatments could help patients feel better. For six months, 70 adults with moderate-to-severe RA either took their usual drugs plus cilostazol or just their usual drugs alone. Re…

This study compared two surgical techniques for moving a high, undescended testicle into the scrotum in young boys. It involved 50 boys over six months old, randomly assigned to receive either a newer 'traction' method or a standard two-stage surgery. The goal was to see which me…

This study tested whether a detailed 3D CT scan could better predict which patients need a temporary tube (a JJ stent) placed before shockwave treatment for kidney stones. Researchers compared the 3D scan method to the standard measurement formula in 56 patients. The goal was to …

This study tested if a procedure called bronchoscopy could help doctors find tuberculosis in the airways of patients when the usual sputum (mucus) tests came back negative. Researchers performed the procedure on 63 adults suspected of having lung TB but with negative sputum tests…

This study tested whether a simple, non-invasive finger monitor (called the peripheral perfusion index) could predict which patients would experience a dangerous drop in blood pressure after receiving spinal anesthesia for leg surgery. Researchers observed 40 healthy adults under…

This study tested whether specific patterns seen on an ultrasound during a lung scope (EBUS) could help doctors tell if swollen chest lymph nodes are cancerous or benign. Researchers looked at 50 adult patients who had the procedure. They compared the ultrasound pictures with res…

This study looked at two ways to quickly figure out if fluid around the lungs (pleural effusion) is caused by cancer or a non-cancerous condition during a medical procedure called thoracoscopy. Researchers compared a doctor's visual inspection of the lung lining with a rapid on-s…

This study tested a scoring system designed to help doctors choose the best treatment for broken leg bones that fail to heal on their own. Researchers scored 60 adult patients based on their specific condition and then treated them according to that score, from simple fixes to co…

This study compared two approaches to prevent urinary tract infections (UTIs) in children after a kidney stone removal procedure called flexible ureteroscopy. Researchers tested whether giving preventive antibiotics worked better than using enhanced sterile techniques and careful…

This study tested whether adding green tea extract to standard medication could help prevent obese children with prediabetes from developing type 2 diabetes. It involved 90 children aged 10-18 and compared the effects of green tea pills plus metformin against metformin alone over…

This study tested whether a daily supplement made from cow's colostrum (the first milk) could help prevent recurring urinary tract infections (UTIs) in children. Sixty children with a history of frequent UTIs were randomly assigned to take either the colostrum supplement or a pla…

This study tested if a special mouth cleaning routine could prevent dangerous lung infections in children on breathing machines in the intensive care unit. Researchers compared regular mouth cleaning to a more thorough method that included toothbrushing with an antiseptic mouthwa…

This study tested whether special mouthwashes containing the amino acids L-arginine or L-glutamine could help reduce the severity of painful mouth sores caused by radiation therapy in head and neck cancer patients. 84 participants were randomly assigned to use one of the amino ac…

This study compared two different ultrasound-guided nerve-blocking techniques for managing pain in children (aged 1-7 years) undergoing hypospadias repair surgery. The goal was to see if a newer method, called a sacral multifidus plane block, works as well as or better than the s…

This study tested whether adding a medication called dexmedetomidine could help reduce the amount of strong pain medication (fentanyl) needed for full-term newborns on breathing machines. Researchers enrolled 40 infants aged 1-28 days who were starting mechanical ventilation. The…

This study compared two different nerve-blocking techniques to relieve pain when positioning patients with broken hips for spinal anesthesia. Forty-two adults scheduled for hip fracture surgery received either a PENG block or a QLB block before their procedure. Researchers measur…

This study compared two safe methods of pain relief for young boys having hypospadias repair surgery. Thirty boys were randomly assigned to receive either a caudal block (lower back injection) or a penile nerve block (groin injection) during surgery. The study found the caudal bl…

This study compared two different nerve block techniques for managing pain after knee replacement surgery. Researchers tested whether a newer method called PASC block works as well as a standard combination of nerve blocks. They measured how much pain medication patients needed i…

This study compared two different nerve block techniques to see which one better controls pain after breast cancer surgery. Researchers tested these methods on 88 women undergoing mastectomy, measuring their pain levels and need for strong painkillers over 24 hours. The goal was …

This study compared two medications, granisetron and pethidine, to see which works better at stopping shivering after spinal anesthesia for cesarean sections. Shivering is a common and uncomfortable side effect that can happen after this type of anesthesia. The trial involved 330…

This study tested if numbing a patient's airway with a spray before heart surgery could help them need less strong pain medication. Using less of these medications might help keep their blood pressure and heart rate more stable during the critical start of the procedure. The goal…

This study tested two different medications to see which one works better at reducing the pain and urinary symptoms people often experience from a ureteral stent. A ureteral stent is a small tube placed after kidney stone surgery to help drainage. 150 patients tried both tadalafi…

This study compared two different nerve-block techniques for managing pain after breast cancer surgery (mastectomy). Researchers tested the methods on 64 female patients to see which provided better and longer-lasting pain relief with fewer side effects. They found that one speci…

This study tested whether adding common medications (dexamethasone or magnesium sulfate) to a standard numbing injection in the lower back could better control pain after hip replacement surgery. Researchers compared how long pain relief lasted and how much extra pain medication …

This study compared two sedation methods to help young children stay still during brain MRI scans. Researchers tested whether a combination using melatonin (a natural sleep hormone) worked as well as the standard chloral hydrate sedative, both given with a mild inhaled anesthetic…

This study compared two different nerve-block techniques to see which one better controls pain for 24 hours after weight loss surgery. Thirty adults undergoing laparoscopic sleeve gastrectomy received either an erector spinae plane block or a thoracic paravertebral block. Researc…

This study compared two different approaches to managing pain during and after gallbladder removal surgery. Researchers tested whether using a combination of non-opioid medications could lead to better recovery than traditional opioid-based pain relief. The study involved 50 adul…

This study tested whether adding melatonin pills to a standard sedative infusion works better than the sedative alone at preventing post-operative delirium (confusion and disorientation) after open brain surgery. One hundred patients undergoing brain surgery were randomly assigne…

This study tested if adding one of two drugs (fentanyl or dexmedetomidine) to a standard spinal anesthetic could help patients recover feeling and movement in their legs faster after minor anal surgery. The goal was to see if this faster recovery allowed patients to meet the crit…

This small study compared two ways of taking molds for a single front-tooth implant: a new digital scan and the traditional method using putty. Researchers wanted to see which method led to better-looking gums around the implant and which was more comfortable for patients. Fourte…

This study tested two different ways to improve pain control after minimally invasive colon surgery. Researchers compared adding either a low dose of ketamine or a fentanyl skin patch to a standard ultrasound-guided nerve block. The goal was to see which combination provided long…

This study compared two different nerve block methods for managing pain during and after hip replacement surgery. Researchers tested whether a newer technique called the PENG block works as well as a more established method called the SFIC block. The goal was to find which approa…

This study tested if adding a nerve treatment during knee replacement surgery helps patients recover with less pain and better function. It compared standard knee replacement surgery to surgery that also included a procedure to block pain signals from knee nerves. The study invol…

This study tested whether a mouth rinse made from sumac, a natural plant extract, could help people with recurrent canker sores. It involved 38 adults with painful mouth ulcers to see if the rinse reduced pain and helped the sores heal faster. Researchers also checked blood marke…

This study tested whether melatonin patches placed on the skin could safely reduce anxiety in children during dental visits. It involved 52 children aged 5-7 who needed dental work. Researchers compared children who received real melatonin patches to those who received placebo st…

This study tested whether adding a low dose of tadalafil (a medication for erectile dysfunction) to the standard drug solifenacin improves symptoms of overactive bladder in women. Researchers compared the two-drug combination against solifenacin alone in 80 women over three month…

This study compared two different types of ultrasound-guided nerve blocks to see which one better controls pain after minimally invasive appendix removal surgery. Researchers tested these pain control methods on 72 adult patients undergoing the procedure. The goal was to find the…

This study tested whether two specific breathing exercises could help adults with mild to moderate asthma breathe better. Sixty Egyptian adults practiced either diaphragmatic breathing or pursed-lip breathing for 20 minutes, twice daily, over 8 weeks. Researchers measured lung fu…

This study tested if rinsing with thyme honey could relieve severe dry mouth in head and neck cancer patients after radiation therapy. 90 patients were randomly assigned to use either a diluted thyme honey rinse or a saltwater rinse several times a day for about two months. Resea…

This small study compared two materials used to attach partial dentures (fake teeth) to a patient's remaining natural teeth. Twelve people with missing back teeth received dentures clipped to their premolars using either a newer computer-designed composite material or a tradition…

This study tested whether a special elimination diet, called an oligoantigenic diet, could reduce core symptoms of ADHD in children. Fifty children aged 6 to 16 were randomly assigned to either follow this restrictive diet or a normal, healthy diet for three months. Researchers m…

This study tested a new way to manage pain after laparoscopic gallbladder removal surgery. Researchers compared a standard numbing medicine (bupivacaine) against the same medicine combined with another drug called dexmedetomidine, which was applied inside the abdomen at the end o…

This study tested if applying cold therapy could reduce pain and inflammation after a root canal procedure for a painful tooth infection. Researchers compared applying an ice pack to the cheek versus rinsing the tooth's root with cold saline, against a standard treatment with no …

This study tested whether adding one of two medications (dexmedetomidine or ketamine) to a standard numbing injection provides better and longer-lasting pain relief after hernia repair surgery. Researchers compared these two combinations against the standard numbing medication al…

This study compared two medications, propofol and dexmedetomidine, to see which works better at preventing agitation when children wake up from anesthesia after squint (eye muscle) surgery. Researchers enrolled 80 children aged 3-7 years to measure restlessness, crying, and confu…

This study looked at whether methotrexate, a common rheumatoid arthritis medication, causes lung problems. Researchers compared 50 Egyptian arthritis patients who either took methotrexate or other arthritis drugs. They found no difference in lung health between the two groups, su…

This study tested how accurately dentists can place dental implants using a computer navigation system compared to traditional methods. Researchers worked with 20 healthy adults who needed implants immediately after tooth removal. They used special 3D scans before and after surge…

This study aimed to find out which of two common dental implant connection types is better at preserving jawbone. Researchers followed 14 male patients with no teeth, comparing bone loss around implants over 9 months using special X-rays. The goal was to gather knowledge to help …

This study looked at whether certain molecules in the blood could help doctors detect chronic kidney disease earlier and predict which patients might not respond well to common anemia treatments. Researchers compared 180 people—60 healthy individuals, 60 with moderate kidney dise…

This completed study looked for a connection between vitamin D levels in the blood and early signs of heart disease in people receiving long-term dialysis. Researchers enrolled 90 adult patients to measure their vitamin D and check for artery hardening. The goal was to gather inf…

This study aimed to see if a simple blood measurement, called the Capillary Leak Index (CLI), could help predict which critically ill patients are most likely to survive after major abdominal surgery for a severe infection. Researchers followed 100 adult patients in intensive car…

This completed study aimed to understand if children with hepatitis C infection—particularly those with thalassemia or who survived childhood cancer—are more likely to develop insulin resistance, a condition that can lead to diabetes. Researchers compared 90 infected children to …

This study aimed to see if a simple brain wave scan before a root canal could help predict which patients might experience more pain afterwards. Researchers recorded brain activity from 100 adults before their procedure and then asked them to track their pain levels. The goal was…

This study looked back at the medical records of 293 women who had surgery to remove uterine fibroids (non-cancerous growths) at a specific hospital. The main goal was to find out how often surgeons had to perform a full hysterectomy (removing the uterus) instead of just removing…

This study looked at whether a simple ultrasound measurement of how much the prostate bulges into the bladder can predict how well men will respond to medication for urinary symptoms. Researchers followed 130 men over six months to see if the initial scan could identify who would…

This study tested whether adding a special geometric guide to 3D mouth scanners could help create more accurate digital models for patients needing a full set of upper dental implants. Researchers compared three different scanning methods on seven patients to see which produced t…