Can dead teeth be brought back to life? new study tests regeneration vs. standard cleaning

NCT ID NCT07609732

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared three approaches for treating dead, infected adult teeth: a regenerative procedure that induces bleeding inside the tooth, standard cleaning and sealing, and a combination. Fifty-four adults with an infected upper premolar were treated and followed for healing and any return of tooth sensation. The goal was to see which method best resolves infection and potentially restores tooth vitality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Regenerative endodontic procedure (bleeding induction) and standard cleaning and shaping
What this could lead to
If successful, this could offer a way to restore vitality in dead adult teeth, potentially avoiding root canals or extractions.
What could go wrong
This is a small, completed trial with only 54 participants, so results may not apply broadly. Regeneration may not reliably restore nerve function or long-term tooth health.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty Of Dentistry Ain Shams University

    Cairo, Cairo Governorate, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.