Which sedative combo is best for stomach scope procedures?

NCT ID NCT07190612

Completed Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested three different drug combinations to sedate patients during upper gastrointestinal endoscopy (a scope procedure to examine the stomach and esophagus). 75 adults were randomly assigned to receive propofol plus either ketamine, dexmedetomidine, or midazolam. Researchers measured how quickly patients woke up and how well they were sedated. The goal is to find the safest and most effective sedation approach for routine endoscopic procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: propofol combined with either ketamine, dexmedetomidine, or midazolam
What this could lead to: If successful, this could help doctors choose the best sedation method for upper GI endoscopy, leading to faster recovery and fewer side effects.
What could go wrong: This is a small, completed Phase 4 trial with only 75 participants, so results may not apply to all patients. The study compares existing drugs, not a new breakthrough.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA UPPER GASTROINTESTINAL ENDOSCOPY

Contacts and locations

Locations

Faculty of Medicine

Cairo, Egypt

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