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Battle of the bright smiles: which technique best hides MIH white spots?

NCT ID NCT07715370

Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial tests three different surface treatments—microabrasion, etch-bleach, and macroabrasion—before applying a resin infiltration procedure to improve the appearance of white spots on permanent front teeth in children aged 8 to 14 with molar incisor hypomineralization (MIH). The goal is to find the most effective, conservative approach to reduce these enamel opacities and improve the child's quality of life. Researchers will measure color change and use a questionnaire to assess how the treatment affects the child's well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
resin infiltration, microabrasion, and etch-bleach procedures
What this could lead to
If successful, this could identify the best minimally invasive technique to improve the look of white spots on front teeth in children with MIH, boosting their confidence.
What could go wrong
This is a small, early-stage trial with only 63 participants, so results may not apply to everyone. The procedures may not fully mask the spots or could cause tooth sensitivity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

63 people

The number who actually took part.

Started

Jul 2024

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

8 to 14 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Cooperative healthy male and female children aged 8 to 14 years. * MIH diagnosed patients according to the criteria of European Academy of Pediatric Dentistry (EAPD) with demarcated enamel opacity that caused esthetic discomfort to them and their guardian, involving at least one maxillary or mandibular permanent incisor. * At least one-third of the affected tooth crown should be visible in the oral cavity. Exclusion Criteria: * Children with behavioral, cognitive, physical, or medical conditions that will affect or complicate the treatment. * Other developmental defects of dental enamel rather than MIH (i.e. dental fluorosis, enamel hypoplasia, amelogenesis imperfecta or Turner's tooth) * Loss of tooth structure due to post-eruptive enamel breakdown or caries. * Periodontal disease of the affected tooth. * Incisors previously subjected to trauma that might lead to loss of tooth structure or compromise the pulp vitality. * Previous preventive, restorative or orthodontic treatment on the affected tooth.

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Conditions

The condition(s) this trial relates to.

Molar Hypomineralization

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Molar incisor hypomineralization

Contacts and locations

Locations

  • Faculty of Dentistry, Ain Shams University

    Cairo, Cairo Governorate, Egypt

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