Shining a light on tooth spots: new pretreatment may boost aesthetic results

NCT ID NCT07753070

First seen Aug 07, 2026 ยท Last updated Aug 07, 2026

Summary

This trial tests whether a special light-guided pretreatment can improve the cosmetic outcome of resin infiltration for teeth affected by molar incisor hypomineralization (MIH), a condition causing white or creamy spots on permanent incisors. The study compares two approaches: one where the tooth surface is roughened and then treated with a bleaching agent, versus roughening alone. The goal is to see if the added step improves the masking of the spots and reduces the time needed for the resin treatment. The trial involves 100 healthy children with mild MIH-related opacities on their front teeth.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
macroabrasion followed by oxidative pretreatment with 5.25% sodium hypochlorite, compared to macroabrasion alone
What this could lead to
If effective, this approach could improve the cosmetic appearance of teeth affected by MIH and shorten the time needed for resin infiltration treatment.
What could go wrong
This is a small, early-stage trial, and results may not apply to all cases. The pretreatment involves chemicals and abrasion, which carry risks of tooth sensitivity or gum irritation.

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Conditions

The condition(s) this trial relates to.

Molar Hypomineralization

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Outpatient Clinic of Pediatric dentistry, Faculty of dentistry, Alexandria University, Egypt

    Alexandria, Egypt

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