New tooth sealant tested for kids with weak enamel

NCT ID NCT07504614

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new pre-etched bioactive sealant against a standard resin sealant for protecting permanent molars in children aged 6-12 who have molar incisor hypomineralization (MIH), a condition that weakens enamel. The trial will check how well each sealant stays on, prevents cavities, and reduces tooth sensitivity. 76 children will be enrolled to see which sealant works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pre-etched bioactive fissure sealant

What this could lead to

If it works, this could offer a better way to protect children's molars affected by MIH from cavities and sensitivity.

What could go wrong

This is a small, early-stage trial with only 76 participants, so results may not apply to everyone. The new sealant might not perform better than the standard one.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Molar Hypomineralization

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jordan University of Science and Technology

    Irbid, Jordan