Daily pills may ease painful stent symptoms
NCT ID NCT07206706
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two drugs—tadalafil and darifenacin—to see which better relieves bladder symptoms and pain caused by ureteric stents. 150 adults who had a stent placed after kidney stone treatment took each drug for three weeks in a crossover design. The goal was to find a more effective and tolerable option for managing these common side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tadalafil and darifenacin
- What this could lead to
- If one drug works better, it could offer a simple daily pill to reduce discomfort from ureteric stents.
- What could go wrong
- This is a small, early-phase trial with only 150 people. Results may not apply to everyone, and side effects like headache or dry mouth are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain Shams University Hospita
Cairo, Cairo Governorate, 1151, Egypt