Melatonin plus sevoflurane may offer safer MRI sedation for young kids
NCT ID NCT06606899
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two ways to sedate preschool children (ages 2-5) for brain MRI scans. One group received oral melatonin and nasal sevoflurane; the other got oral chloral hydrate and nasal sevoflurane. The goal was to see which combination worked better and more safely. The trial involved 60 children and has already been completed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Melatonin and chloral hydrate (sedatives)
- What this could lead to
- If successful, this could point toward a safer, more effective sedation option for young children undergoing MRI scans.
- What could go wrong
- This is a small, completed trial with only 60 participants, so results may not apply to all children. The primary outcome was assessed post-hoc, which reduces reliability.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SEDATION FOR CHILDREN UNDERGOING MRI are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain shams university hospitals
Cairo, Egypt