Can a simple infusion make sinus surgery safer and clearer?

NCT ID NCT06848764

Completed Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This trial tests whether lidocaine or dexmedetomidine, given as infusions during functional endoscopic sinus surgery, can reduce bleeding and improve the surgeon's view. Forty adults aged 18 to 65 scheduled for elective sinus surgery will receive one of the two drugs after anesthesia. The main goal is to see which drug leads to less bleeding, measured by a standard surgical field scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine or dexmedetomidine given as an infusion during surgery
What this could lead to: If one drug works better, it could help surgeons see more clearly and reduce complications during sinus surgery.
What could go wrong: This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. Both drugs have side effects like low blood pressure or slow heart rate.

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Conditions

The condition(s) this trial relates to.

Blood Loss, Surgical

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEXMEDETOMIDINE FUNCTIONAL ENDOSCOPIC SINUS SURGERY INFUSION INTRAOPERATIVE BLEEDING LIDOCAINE

Contacts and locations

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Locations

Ain Shams University

Cairo, 11591, Egypt

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