Methotrexate off the hook? no lung harm found in RA study
NCT ID NCT07360340
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 50 Egyptian patients with rheumatoid arthritis to see if methotrexate affects lung health. Half were taking methotrexate, and half were on other treatments. Researchers used lung function tests and CT scans to check for lung disease. They found no difference between the two groups, suggesting methotrexate may not cause lung problems in these patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Methotrexate
- What this could lead to
- If confirmed, this could reassure patients that methotrexate may not increase the risk of lung problems in rheumatoid arthritis.
- What could go wrong
- This was a small, single-center study with only 50 participants. Results may not apply to all populations or account for long-term effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of medicine, Ain Shams University
Cairo, Egypt