Can a Doctor's eye and a quick slide test diagnose lung fluid cancer in real time?
NCT ID NCT07286045
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at two ways to quickly tell if fluid around the lungs (pleural effusion) is cancerous during a procedure called thoracoscopy. Doctors visually inspected the lining of the lung and also did a rapid test on biopsy samples right in the procedure room. The goal was to see if these methods could give an accurate diagnosis faster than waiting for standard lab results. The study involved 33 adults with undiagnosed pleural effusion.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors diagnose pleural effusion faster and more accurately during thoracoscopy, potentially reducing the need for repeat procedures.
- What could go wrong
- This is a small, completed observational study with only 33 participants. The methods may not be accurate enough to replace standard lab testing, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
33 people
The number who actually took part.
- Started
-
Dec 2023
- Finished
-
Dec 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients (\>18 years) with undiagnosed exudative pleural effusion undergoing medical thoracoscopy.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria included adult patients (\>18 years) with undiagnosed pleural effusion undergoing medical thoracoscopy. Exclusion Criteria: Exclusion Criteria, while Medical thoracoscopy is generally safe; patients with the following conditions were excluded in accordance with reported contraindications (Jin et al., 2020): 1. Absolute contraindications: * Refusal to participate in the study. * Extensive pleural adhesions (e.g., pleural fibrosis, post-infection, or prior pleurodesis). * Inadequate pleural space for thoracoscopy. 2. Relative contraindications\*\* * Coagulopathy (platelet count \<60 × 10⁹/L or INR \>1.2), unless corrected prior to the procedure. The use of aspirin and clopidogrel was not considered a contraindication. * Inability to tolerate the lateral decubitus position. * Unstable hemodynamic status. * Severe hypoxemia requiring high-flow oxygen therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain shams university
Cairo, Egypt
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