A simple baking soda pill may protect dialysis Patients' blood vessels

NCT ID NCT07765459

Completed Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This trial tests whether taking oral sodium bicarbonate to correct metabolic acidosis can slow the buildup of calcium in the blood vessels of people on long-term hemodialysis. The study will include 40 adults who have been on dialysis for over six months and have low bicarbonate levels. Researchers will measure changes in carotid artery thickness using ultrasound, along with blood calcium and phosphorus levels, to see if this simple intervention offers cardiovascular benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oral sodium bicarbonate
What this could lead to: If successful, this could point toward a simple, inexpensive way to reduce cardiovascular risk in people on dialysis.
What could go wrong: This is a small, early-phase trial, so results may not be conclusive. Sodium bicarbonate can affect electrolyte balance, requiring careful monitoring.

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Conditions

The condition(s) this trial relates to.

Acidosis chronic kidney disease end stage renal failure metabolic acidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

END STAGE RENAL DISEASE (ESRD) METABOLIC ACIDOSIS

Contacts and locations

Locations

Ainshams university

Cairo, Egypt, 11111, Egypt

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