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Pill vs. machine: which fixes acid imbalance better for dialysis patients?

NCT ID NCT07688434

Not yet recruiting Disease control Sponsor: University of Sfax Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 22, 2026 · Updated 7 times

Summary

This study tests two common methods to treat metabolic acidosis—a condition where blood becomes too acidic—in people on long-term hemodialysis for kidney failure. One group takes oral sodium bicarbonate capsules, while the other gets a higher bicarbonate concentration in their dialysis fluid. Over four weeks, researchers measure changes in blood bicarbonate levels to see which approach works better and is safer. The results will help design a larger, more definitive trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sodium bicarbonate
What this could lead to
If one method works better, it could improve acid balance and reduce complications in dialysis patients.
What could go wrong
This is a small pilot study with only 37 participants, so results may not apply broadly. Both treatments may cause side effects like high sodium or blood pressure changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acidosis chronic kidney disease end stage renal failure metabolic acidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC HEMODIALYSIS END-STAGE RENAL DISEASE (ESRD) METABOLIC ACIDOSIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Social security fund polyclinic

    Sfax, 3080, Tunisia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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