Lab-Made blood vessel could free dialysis patients from catheters

NCT ID NCT05908084

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial tests a lab-grown blood vessel (ATEV) against the standard surgically created fistula in 121 women with end-stage kidney disease who need dialysis. The goal is to see if the ATEV allows more days without a catheter and reduces infections over 12 months. If successful, it could offer a safer, more convenient option for dialysis access.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acellular Tissue Engineered Vessel (ATEV) – a lab-grown blood vessel made from human cells that are removed, leaving a collagen tube

What this could lead to

If it works, this could give women on dialysis a better option for blood access, reducing time with catheters and lowering infection risk.

What could go wrong

This is a relatively small Phase 3 trial (121 women). The ATEV may not perform better than the standard fistula, and there are risks of clotting, infection, or vessel failure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Access Research Institute

    Brooksville, Florida, 34613, United States

  • Ambulatory Care Pavilion Westchester Medical Center

    Valhalla, New York, 10595, United States

  • American Access Care of Miami, LLC

    Miami, Florida, 33156, United States

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Capital Health Medical Center- Hopewell

    Pennington, New Jersey, 08534, United States

  • Cataract & Surgery Center Lubbock

    Lubbock, Texas, 79410, United States

  • Dell Seton Medical Center at The University of Texas at Austin

    Austin, Texas, 78701, United States

  • Denver Health and Hospital Authority

    Denver, Colorado, 80204, United States

  • Dr. Ruben Villa__Nephrology

    Lubbock, Texas, 79407, United States

  • Duke Regional Hospital

    Durham, North Carolina, 27704, United States

  • El Centro Regional Medical Center

    El Centro, California, 92243, United States

  • Georgia Nephrology

    Atlanta, Georgia, 30046, United States

  • Grady Memorial Hospital

    Atlanta, Georgia, 30303, United States

  • Honor Health Scottsdale Shea Medical Center

    Scottsdale, Arizona, 85260, United States

  • IU Health Bloomington Hospital

    Bloomington, Indiana, 47408, United States

  • Jacob's Medical Center at UC San Diego Health

    La Jolla, California, 92037, United States

  • John Hopkins University School of Medicine

    Baltimore, Maryland, 21287, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • New York-Presbyterian Queens_The Lang Center for Research & Education

    Flushing, New York, 11355, United States

  • Rutgers University_Medical

    Newark, New Jersey, 07103, United States

  • San Antonio Vascular and Endovascular Clinic PLLC

    San Antonio, Texas, 78221, United States

  • St.Joseph's University Medical Center

    Paterson, New Jersey, 07503, United States

  • Surgical Specialists of Charlotte

    Charlotte, North Carolina, 28207, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • The San Antonio Vascular and Endovascular Clinic

    San Antonio, Texas, 78221, United States

  • USF Health South Tampa

    Tampa, Florida, 33606, United States

  • University of FL Health Heart and Vascular Hospital

    Gainesville, Florida, 32608, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Tennessee Medical Center

    Knoxville, Tennessee, 37920, United States

  • Wake Forest University School of Medicine_Atrium Health Wake Forest Baptist

    Winston-Salem, North Carolina, 27157, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, 06519, United States