Heart drug showdown: which works best when kidneys also fail?
NCT ID NCT07186062
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study looked at 60 adults with acute decompensated heart failure and kidney impairment. Researchers compared three intravenous heart medications—levosimendan, dobutamine, and milrinone—to see which one improved heart and kidney function best. The goal was to find the most effective option for managing this difficult combination of conditions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Levosimendan, dobutamine, and milrinone (heart-failure medications given intravenously)
What this could lead to
If one drug proves clearly better, it could guide doctors to choose the most effective treatment for heart failure patients who also have kidney issues.
What could go wrong
This is a small, completed study (60 people) that compares existing drugs, so it won't produce a new treatment. Results may not apply to all patients, and each drug carries risks like low blood pressure or heart rhythm problems.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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faculty of medicine Ain shams University
Cairo, Egypt