C-Section shivering showdown: granisetron vs pethidine
NCT ID NCT06513806
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 4 trial tested two drugs—granisetron and pethidine—to treat shivering that can occur after spinal anesthesia during cesarean sections. 330 women aged 18-45 who had shivering after their C-section were given one of the two drugs. The main goal was to see how well each drug stopped the shivering, with secondary checks on pain and side effects like nausea.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- granisetron and pethidine
- What this could lead to
- If successful, this could show that granisetron is a safe and effective alternative to pethidine for stopping shivering after C-sections.
- What could go wrong
- This is a completed Phase 4 trial, so results are known. However, it only compares two drugs for a temporary side effect, not a cure or major breakthrough.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ain Shams University
Cairo, Egypt
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