C-Section shivering showdown: granisetron vs pethidine
NCT ID NCT06513806
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 29 times
Summary
This completed Phase 4 trial tested two drugs—granisetron and pethidine—to treat shivering that can occur after spinal anesthesia during cesarean sections. 330 women aged 18-45 who had shivering after their C-section were given one of the two drugs. The main goal was to see how well each drug stopped the shivering, with secondary checks on pain and side effects like nausea.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ain Shams University
Cairo, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
granisetron and pethidine
What this could lead to
If successful, this could show that granisetron is a safe and effective alternative to pethidine for stopping shivering after C-sections.
What could go wrong
This is a completed Phase 4 trial, so results are known. However, it only compares two drugs for a temporary side effect, not a cure or major breakthrough.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.