Rare gut condition: which surgery works best?

NCT ID NCT06970093

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two surgeries—One Anastomosis Gastric Bypass and Duodenojejunostomy—for treating Superior Mesenteric Artery Syndrome (SMAS), a rare condition where the duodenum is compressed, causing severe nausea, vomiting, and weight loss. Twenty participants were randomly assigned to one surgery and followed for 12 months to see which better improves symptoms and nutrition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
One Anastomosis Gastric Bypass (OAGB) and Duodenojejunostomy (DJ) surgeries
What this could lead to
If this trial succeeds, it could show which surgery is more effective for treating SMAS, helping patients get better symptom relief and nutritional recovery.
What could go wrong
This is a small study with only 20 participants, so results may not apply to everyone. Both surgeries are invasive and carry risks like infection or complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ain Shams University Hospitals

    Cairo, Cairo Governorate, 11566, Egypt

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Other studies related to the condition(s) this trial covers.