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Can popular Weight-Loss drugs alter breastmilk supply?

NCT ID NCT07720414

Recruiting now Knowledge-focused Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study investigates whether injected GLP-1 receptor agonists, such as semaglutide, affect breastmilk production and its nutritional makeup in breastfeeding mothers. Participants will have their milk production measured before and after starting the medication, and milk samples will be analyzed for fat and other nutrients. The goal is to understand if these weight-loss drugs are safe for breastfeeding women and their infants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
injected GLP-1 receptor agonists (e.g., semaglutide, tirzepatide)
What this could lead to
If it works, this could help breastfeeding mothers and doctors make informed decisions about using GLP-1 drugs after pregnancy.
What could go wrong
This is a small, early-stage study with only 18 participants, so results may not apply to all mothers. The drugs are prescribed by personal doctors, not the study team, which limits control.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Breast Feeding lactation disease Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LACTATION WEIGHT LOSS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Colorado Anschutz School of Medicine

    RECRUITING

    Aurora, Colorado, 80045, United States

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