Drug combo may cut opioid use after lung surgery

NCT ID NCT06837519

Completed Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This trial tests whether giving lidocaine, dexmedetomidine, or both during video-assisted thoracoscopic surgery (VATS) can reduce pain and the need for morphine afterward. Adults undergoing VATS under general anesthesia will receive one of the two drugs or a combination. The main goal is to see how much morphine patients need after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine and dexmedetomidine infusions, alone or combined
What this could lead to: If successful, this combination could offer better pain control and reduce the need for morphine after lung surgery.
What could go wrong: This is a small, early-phase trial, so results may not apply broadly. Both drugs can cause side effects like low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEXMEDETOMIDINE INFUSION LIDOCAINE PERIOPERATIVE PAIN VIDEO-ASSISTED THORACOSCOPIC SURGERY

Contacts and locations

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Locations

Ain Shams University

Cairo, 11591, Egypt

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