Water pill during kidney stone surgery may flush out more fragments

NCT ID NCT07336485

Completed Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tested whether giving a diuretic (furosemide) during flexible ureteroscopy for medium-sized kidney stones (up to 30 mm) reduces leftover stone fragments. 2000 adults were randomly assigned to receive furosemide or standard care. Stone-free status was checked with a CT scan four weeks later. The goal is to see if forced urine production helps clear tiny fragments that might otherwise grow or cause symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: furosemide (a diuretic, or water pill)
What this could lead to: If it works, this could become a standard step during kidney stone surgery to help clear more stone fragments, reducing the need for follow-up procedures.
What could go wrong: This is a completed trial, but the results are not yet widely adopted. The benefit may be small or not apply to all stone types or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY STONES

Contacts and locations

Locations

Ain Shams University Hospitals (Urology Department)

Cairo, Cairo Governorate, 11511, Egypt

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