Chill out: cold therapy may ease root canal pain

NCT ID NCT07138365

First seen Feb 19, 2026 · Last updated Jun 10, 2026 · Updated 17 times

Summary

This study tested if applying cold therapy (cryotherapy) after a root canal can reduce pain and inflammation. 180 adults with infected lower premolars were divided into groups: one got a cold pack on the cheek, another got a cold saline rinse inside the tooth, and a third got standard care. Researchers measured pain levels and a chemical linked to inflammation (substance P) to see which method worked best.

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Contacts and locations

Locations

  • Ain Shams University

    Cairo, Egypt

Conditions

Explore the condition pages connected to this study.