Ice pack or cold rinse: simple trick to beat root canal pain?

NCT ID NCT07138365

Completed Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether applying cold therapy (cryotherapy) inside the mouth or inside the tooth itself can reduce pain and inflammation after root canal treatment. Thirty adults with painful tooth infections received either an oral cold pack, a cold saline rinse inside the tooth, or standard care. Researchers measured pain levels and a chemical linked to inflammation. The goal is to find a simple, drug-free way to manage post-treatment discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cryotherapy (cold packs or cold saline irrigation)
What this could lead to: If it works, this could offer a simple, drug-free way to manage pain after root canal treatment.
What could go wrong: This is a small, early-stage study with only 30 participants, so results may not apply to everyone. The effect may be small or no better than standard care.

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Conditions

The condition(s) this trial relates to.

Inflammation inflammatory disease Pain, Postoperative periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLAMMATION POST-OPERATIVE PAIN

Contacts and locations

Locations

Ain Shams University

Cairo, Egypt

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