Mayo Clinic

This study tested whether the drug Obinutuzumab could help adults with a specific, difficult-to-treat kidney disease called primary FSGS. It involved 20 participants whose disease had not improved with standard treatments like steroids or other immunosuppressants. Researchers mea…

This study tested an inhaled drug called treprostinil in people with high blood pressure in their lungs caused by scarring lung disease. Researchers wanted to understand how the drug helps during exercise and affects quality of life after three months of use. The study involved 2…

This study tested a shorter, more intense form of radiation therapy for men whose prostate cancer had a high risk of returning after surgery. The goal was to see if this faster treatment schedule worked as well as standard, longer radiation at keeping the cancer from coming back,…

This study tested whether a vaccine called PDS0101, given alone or with an immunotherapy drug (pembrolizumab), could help shrink tumors in patients with HPV-linked throat cancer before they had surgery. The goal was to see if this approach could make the tumors smaller, potential…

This study tested two different laser eye treatment approaches for controlling eye pressure in people with glaucoma. Researchers compared treating the nasal side versus the bottom side of the eye with the same laser procedure. The goal was to find which approach works better to r…

This study tested whether giving radiation therapy twice daily along with a chemotherapy drug called docetaxel could better control cancer that returns after surgery for HPV-related throat cancer. The trial involved 81 patients who had their tumors surgically removed but were at …

This study tested whether daily dietary sugar supplements could improve health in children with congenital disorders of glycosylation (CDG), a rare genetic condition. Researchers followed 20 children who were already taking or planning to take these supplements. They measured gro…

This study tested a new remote health coaching system for adults with severe obesity and obstructive sleep apnea. The goal was to see if people could use the devices at home and if the program was helpful for making lifestyle changes. Researchers gathered feedback from 17 partici…

This study tested a 12-week virtual program that combined mindfulness exercises with weight management support for obese cancer survivors. The goal was to see if this approach was practical and could help improve mood, reduce stress, and promote weight loss, which may lower the r…

This study aimed to see if a monthly injection called erenumab could prevent headaches from becoming a long-term problem after a mild concussion. It involved 6 adults who had developed headaches within 8 weeks of their head injury. The goal was to see if the treatment could reduc…

This small, early-stage study from the Mayo Clinic aimed to see if giving stem cells through an IV was safe and possible for people with severe COPD. It involved 15 adults with advanced lung disease to check for any immediate negative reactions. The main goal was to learn if the …

This study analyzed health records of over 380,000 adults with type 2 diabetes to compare four common second-line medications. Researchers wanted to see which drug class—GLP-1RAs, SGLT2is, DPP-4is, or sulfonylureas—was most effective at preventing major heart problems like heart …

This study tested whether doing cardiac rehabilitation at home using a mobile app works as well as traditional clinic visits. Researchers compared three approaches: clinic-only rehab, clinic plus app support, and app-only remote rehab. They measured heart health, fitness, and hos…

This study tested whether using existing social networks could help people in Hispanic and Somali immigrant communities lose weight and improve their heart health. Researchers worked with 475 participants in Minnesota to see if group support within their communities led to better…

This small pilot study tested a new, targeted laser treatment for men with low-to-intermediate risk prostate cancer. Using real-time MRI guidance, doctors aimed to precisely heat and destroy only the cancerous tumor area, sparing the rest of the prostate. The main goals were to s…

This completed Phase 2 trial tested how well the drug ixazomib works, both alone and combined with other medications, for people with multiple myeloma that has returned after previous treatment. The study involved 165 participants and aimed to measure how many patients responded …

This study tested whether using a special water bottle nozzle daily for 8 weeks could help control obstructive sleep apnea and reduce snoring. The nozzle was designed to provide tongue exercise (myofunctional therapy) as people drank their daily water. Researchers measured change…

This small pilot study from the Mayo Clinic aimed to see if people with chronic non-cancer pain could have their opioid medication dose very slowly reduced without making their pain, mood, or daily life worse. It compared a slow tapering plan to continuing the usual opioid dose. …

This study tested whether a home-based pulmonary rehabilitation program, supported by technology and health coaching, helps people stick with their recovery plan better than being referred to a traditional center-based program after a COPD-related hospital stay. It involved 296 a…

This study tested a combination of two drugs, futibatinib and pembrolizumab, for people with advanced liver cancer that had spread and stopped responding to initial treatment. The goal was to see if the combination could help control the cancer's growth and extend the time before…

This small, completed study from the Mayo Clinic tested whether people with a specific form of Eosinophilic Esophagitis (EoE) triggered by milk could safely eat baked milk, like in muffins or pizza. The goal was to see if this could help expand their diets without causing a flare…

This study tested whether adding a heat treatment (Hybrid Argon Plasma Coagulation) to a stomach-stitching procedure (Endoscopic Sleeve Gastroplasty) leads to better weight loss results. It involved 45 adults with obesity who had not succeeded with diet and exercise alone. Resear…

This study tested a new approach for early-stage breast cancer. It gave patients a shorter, more intense course of radiation to the whole breast *before* their surgery, instead of the usual longer course given after. The goal was to see if this method could completely eliminate t…

This study tested whether a shorter, 15-session course of proton radiotherapy is as safe and effective as a standard 25-session course for patients who had a mastectomy and need radiation to the chest wall and lymph nodes. It involved 88 women with breast cancer and aimed to see …

This study tested a new combination of drugs for men with advanced prostate cancer that had spread and was no longer responding to standard hormone-blocking treatments. It combined a pill (enzalutamide) with two targeted antibody drugs given as an injection to see if attacking th…

This study tested whether adding the drug daratumumab before and after a stem cell transplant could help patients with multiple myeloma achieve deeper remission. The trial involved 49 patients eligible for transplant and measured whether cancer cells became undetectable after tre…

This study tested whether taking the drug ibrutinib as a long-term maintenance treatment could eliminate tiny, hard-to-detect amounts of cancer that remain after initial therapy for chronic lymphocytic leukemia (CLL). It involved 35 patients who had responded to their first treat…

This early-stage trial tested a combination of two existing drugs, auranofin and sirolimus, for patients with advanced or returning lung cancer who had no other standard treatments left. The main goals were to find the safest dose and see if the drugs could slow the cancer's grow…

This study followed 65 glaucoma patients for one year after they received a specific laser treatment called MP-TSCPC. Researchers wanted to see how well this laser procedure lowered eye pressure and reduced the need for daily eye-drop medications. They tracked patients' vision, e…

This study tested whether a virtual reality-based cardiac rehabilitation program works as well as traditional in-person rehab for people recovering from heart events. Nearly 3,000 participants across the US tried either the virtual program or standard care for 12 weeks. The virtu…

This small, early study tested if combining two immune-boosting treatments could help control advanced melanoma. Seven patients with stage IIIB-IV skin cancer that couldn't be surgically removed received pembrolizumab (an IV drug) and applied imiquimod (a cream) to skin lesions. …

This small, early-stage study tested a personalized vaccine for patients with advanced ovarian, fallopian tube, or primary peritoneal cancer. The vaccine was made from a patient's own white blood cells, trained to target a protein found on cancer cells. The main goals were to che…

This study tested whether a higher dose of proton beam radiation works better than a standard dose when combined with chemotherapy for patients with inoperable stage 2 or 3 non-small cell lung cancer. Twenty patients were randomly assigned to receive either 60 Gy or 72 Gy of prot…

This Mayo Clinic study tested whether giving ultra-high doses of water pills (diuretics) is safe and works better than standard doses for people hospitalized with a sudden, severe worsening of heart failure. The small, 20-person pilot trial compared how much fluid patients lost a…

This small, completed study explored whether a medication called rimegepant could help prevent cluster headaches, which are extremely painful and often called 'suicide headaches.' Twenty adults with diagnosed cluster headaches took rimegepant every other day for eight days. Resea…

This study tested a shorter radiation treatment for men with early-stage prostate cancer. Instead of the usual 8+ weeks of treatment, participants received just 5 proton radiation sessions over two weeks. Researchers tracked side effects and quality of life for five years to see …

This study looked at whether using a medication called sugammadex during liver transplant surgery helps patients wake up with less muscle weakness. Researchers monitored 97 liver transplant patients using a special device that measures muscle response. The goal was to see if this…

This study tested whether adding the hormone therapy fulvestrant to a new drug called alisertib works better than alisertib alone for women with advanced breast cancer that has spread and stopped responding to standard hormone treatments. It involved 96 postmenopausal women. Rese…

This study tested a new ventilator guidance system called VentCoach, designed to better protect patients' lungs while they are on breathing machines in the intensive care unit. Researchers compared VentCoach to the standard ventilator settings currently used in the hospital. The …

This small study tested whether delivering butyrate—a natural compound—directly to the colon could help people with type 1 diabetes. Researchers wanted to see if this approach could make the body respond better to insulin and lower blood fat levels. Six adults with type 1 diabete…

This small, early-stage study from the Mayo Clinic tested whether it is safe and practical to treat knee osteoarthritis by injecting a person's own processed fat cells into the joint. Nine participants with moderate arthritis received the injection to see if it caused any serious…

This Mayo Clinic study explored whether two common diabetes medications could help control symptoms of Parkinson's disease and Lewy body dementia. The trial involved 18 patients who had these brain conditions along with mild diabetes or blood sugar issues. Researchers tested if t…

This study tested whether a new artificial intelligence (AI) tool could help find serious liver disease earlier. The AI analyzed routine electrocardiogram (ECG) heart tests from adult patients to look for hidden signs of liver scarring. Researchers compared whether doctors using …

This study tested whether a specific type of MRI scan, called ZTE imaging, can better visualize breast biopsy markers made of bone cement compared to the standard metal markers. Twenty participants with breast cancer underwent their standard breast MRI scans. Radiologists then co…

This study tested whether a new type of PET scan could improve how doctors monitor advanced liver cancer during immunotherapy. Researchers used a special radioactive tracer designed to stick to liver cancer cells to see if the scans provided a clearer picture of how the cancer wa…

This study tested whether a special combined PET/MR scan could help doctors see amyloid protein buildup in the nerves of patients with amyloidosis. Researchers compared scan results from 8 patients with confirmed nerve amyloidosis to patients with other nerve diseases. The goal w…

This study tested whether ultrasound imaging could detect early signs of carpal tunnel syndrome by measuring how tissues move inside the wrist. Researchers compared ultrasound measurements in people with and without carpal tunnel syndrome to see if changes in connective tissue th…

This study tested whether a mobile AI-powered heart monitor could help screen close relatives of people with a heart muscle condition called dilated cardiomyopathy. Researchers gave 119 family members a portable ECG device that connects to a smartphone and uses artificial intelli…

This study tested whether adding a special type of PET scan (called 18F-DOPA-PET) to standard MRI could help doctors more accurately plan radiation therapy for people with newly diagnosed malignant brain tumors (gliomas). The goal was to see if this combined imaging approach coul…

This study tested whether a self-collected vaginal swab kit could accurately detect HPV, the virus that causes cervical cancer, compared to the standard test collected by a doctor. Over 200 women at Mayo Clinic used the kit and then had the standard exam to compare results. The g…

This study aimed to develop a new test that analyzes chemicals in a person's breath to help diagnose diseases. Researchers collected breath samples from 46 people, including healthy volunteers and patients with liver disease or COVID-19. The goal was to see if unique breath 'fing…

This study tested whether 3D surface scans could replace standard CT scans for planning electron radiation therapy for cancer. Researchers compared the accuracy of treatment plans created from 3D scans versus traditional CT scans in 26 adult patients. The goal was to see if this …

This study tested whether a simple, non-invasive brain wave recording (EEG) could help identify Alzheimer's disease at various stages. Researchers collected EEG data from 29 people, including those with no symptoms but at genetic risk, mild memory problems, and different stages o…

This study tested whether a new artificial intelligence (AI) tool could help doctors diagnose a serious heart condition called cardiac amyloidosis earlier. The tool analyzes standard electrocardiogram (ECG) heart tests. Researchers compared diagnosis rates between doctors who use…

This study aimed to find out whether people with non-muscle invasive bladder cancer prefer a simple urine test or a traditional scope procedure for monitoring their condition. Researchers asked 107 patients who tried both methods about their preferences, satisfaction, and quality…

This study aimed to see if a new, broad metabolomic testing method could better diagnose rare inborn errors of metabolism than older tests. Researchers analyzed leftover samples from 240 people with these genetic conditions. The goal was to find better biomarkers to help identify…

This small study tested whether a simple, non-invasive finger sensor could detect active internal bleeding in the stomach or intestines. Researchers monitored tiny changes in blood flow in the finger of 13 patients undergoing an emergency scope procedure for suspected bleeding. T…

This study tested a new ultrasound technique that measures how stiff and stretchy a breast mass is. The goal was to see if this 'Nonlinear Elasticity Mapping' could help doctors better tell if a mass is cancerous or benign without always needing a biopsy. The study involved 172 p…

This study tested a new type of imaging scan to see if it could better find and stage liver cancer. Researchers gave 52 patients a special radioactive tracer and then performed a combined PET/MRI or PET/CT scan. The goal was to see if this new scan method could improve upon curre…

This study tested a new imaging machine called the Veriton SPECT/CT system. Researchers compared it to a standard gamma camera to see if it could take clearer pictures during nuclear medicine exams. The goal was to evaluate if this new technology provides better image quality for…

This study tested a new AI tool, called DermAI, designed to help people read their own skin patch allergy test results at home. Researchers wanted to see if the AI's readings matched those of human experts and if the at-home testing process was practical for participants. The goa…

This study tested whether a new type of PET scan (using a tracer called 18F-FDOPA) could help doctors more accurately see brain tumors. The goal was to improve planning for surgery and radiation therapy by comparing the scan images directly to tumor samples taken during surgery. …

This study tested whether adding a newer imaging method called molecular breast imaging (MBI) to standard 3D mammography (DBT) helps find more invasive breast cancers in women with dense breast tissue. Over 3,000 women aged 40-75 with dense breasts underwent both screening tests …

This study tested whether a new 3D ultrasound test called QTI could work as well as MRI for breast cancer screening in women at high lifetime risk. Researchers compared both tests in 26 women to see if QTI could detect concerning findings effectively. The goal was to determine if…

This study tested whether an education program about HPV (human papillomavirus) could increase the number of underserved adults who started and finished a free HPV vaccine series. It involved 100 low-income, uninsured patients aged 18-45 at a clinic in Florida. The goal was to se…

This study aimed to prevent second ACL tears in young athletes who had already undergone ACL reconstruction surgery. Researchers worked with 150 athletes aged 13-30 to identify movement patterns that put them at high risk for re-injury. They then tested whether personalized, targ…

This large study aimed to find the best way to prevent strokes in people who have a major blockage in their neck (carotid) artery but have not yet had stroke symptoms. Over 2,400 participants were randomly assigned to receive either intensive medication alone, medication plus a s…

This study tested if letting critically ill patients on breathing machines control their own sedation medicine (using a button) works better than having nurses manage it. Researchers wanted to see if this self-management approach could reduce patient anxiety, shorten the time nee…

This study tested whether a short, calming virtual reality (VR) experience could help lower blood pressure and reduce anxiety for people at the doctor's office. 79 adults who were already scheduled for a special 24-hour blood pressure test tried a 5-minute VR nature scene during …

This pilot study tested a new support program designed to help rural-dwelling and Hispanic cancer survivors manage their chronic pain. The program connected 51 participants with a care team by phone or video to create personalized pain management plans. Researchers aimed to refin…

This small, exploratory study tested whether an existing medication called dupilumab could help reduce severe, chronic itching in adults with liver disease. Nine participants received the drug for 18 weeks while researchers tracked their itch intensity and quality of life. The go…

This small Mayo Clinic study tested whether an injection made from a patient's own processed blood plasma could safely reduce pain and improve function in people with moderate knee osteoarthritis. Twenty participants with ongoing knee pain received the injection and were followed…

This study tested a 2-day pain management program for breast cancer survivors experiencing joint and muscle pain as a side effect of their hormone therapy (aromatase inhibitors). The program used counseling, education, and coping strategies to help 105 participants better manage …

This study tested a new system that uses patients' electronic health records to help manage common and severe cancer symptoms like pain, fatigue, anxiety, and sleep problems. Over 50,000 adult cancer patients participated. The goal was to see if better symptom management could im…

This study tested whether it was practical for midlife women with sleep problems to use a special headband that senses brain activity. The goal was to see if using this device could help improve their sleep quality. Researchers measured changes in sleep, stress, anxiety, and qual…

This Mayo Clinic study tested whether a series of pre-recorded hypnotherapy sessions, delivered through a smartphone app over 12 weeks, could help reduce the severity of bloating. The trial involved 27 adults who experienced bloating as a main symptom, tracking their progress for…

This study tested whether using artificial intelligence (AI) to plan radiation therapy could reduce side effects for people with head and neck cancer. Over 200 patients were randomly assigned to have their radiation planned either with the help of an AI tool or using the standard…

This study tested whether a cream containing cannabidiol (CBD) could help reduce painful nerve damage in the hands and feet caused by chemotherapy. Forty adult cancer patients with this condition applied either the CBD cream or a placebo cream for two weeks. The goal was to see i…

This small, early-stage study from the Mayo Clinic explored whether varenicline, a medication used to help people quit smoking, could reduce abdominal pain and sensitivity in people with irritable bowel syndrome (IBS). Eight adults with IBS-related pain participated. Researchers …

This study tested whether a specific shoulder stretch, called the 'sleeper stretch,' could help CrossFit athletes. Researchers wanted to see if the stretch improved shoulder movement, strength, and upper body performance while reducing pain. They compared results in 26 active Cro…

This study tested whether regular phone check-ins and support from care managers could help people with advanced cancer stay mobile and manage pain. Over 500 participants with stage 3 or 4 cancer were assigned to different levels of phone-based support for six months. The goal wa…

This study tested whether a nasal spray made with rose geranium and sesame oil works better than a simple saline spray to relieve nose symptoms in cancer patients on chemotherapy. Over 100 adult patients with symptoms like dryness, pain, or bleeding used one of the two sprays for…

This small, completed study tested if a non-invasive device that stimulates a nerve in the neck could help manage symptoms in teenagers newly diagnosed with POTS. Over two months, researchers compared the device's effects against standard recovery advice, looking at symptom sever…

This Mayo Clinic study tested whether a small electrical stimulation to a part of the inner ear could provide short-term relief from severe, disruptive tinnitus (ringing in the ears). The 25 participants had severe, one-sided tinnitus that other treatments hadn't helped. The rese…

This small pilot study from Mayo Clinic tested whether weighted blankets could help reduce agitation and distressing symptoms in people with dementia. Researchers gave specially weighted blankets to 30 hospitalized patients with dementia and measured changes in their agitation, a…

This study compared two different ways to manage pain after a scheduled cesarean delivery. Researchers tested whether giving methadone through an IV was as effective as giving morphine directly into the spinal fluid. They measured how much additional pain medication women needed …

This study compared two prescription numbing creams to see which better reduces pain during a common laser treatment for sun-damaged skin. Researchers tested each cream on a different half of the face in 22 participants before their laser procedure. The main goal was to measure w…

This study tested whether distance Reiki therapy, delivered via video call, could improve quality of life and possibly affect the immune system in people with multiple myeloma. Thirty patients were divided into groups receiving real Reiki, fake (sham) Reiki, or no additional Reik…

This study tested whether taking a once-daily, extended-release version of the anti-rejection drug tacrolimus causes fewer side effects and is easier to stick with than the standard twice-daily version. Researchers enrolled 261 adult kidney transplant recipients to compare sympto…

This study tested a program called 'Mates in Motion' to see if it's practical and helpful for cancer patients and their live-in partners. The program taught couples communication and teamwork skills to support each other in staying physically active during intensive treatments li…

This study tested whether a medication called PB could help reduce excessive urine production in adults with certain kidney conditions. It included 36 adults who produce very large amounts of urine daily due to inherited conditions, polycystic kidney disease treatment, or previou…

This Mayo Clinic study tested whether a simple, drug-free technique called acupressure could help reduce anxiety in people receiving chemotherapy for cancer. Thirty adult patients who reported anxiety during their chemo treatments received short acupressure sessions from a nurse.…

This small study from the Mayo Clinic explored whether adding brief advice about diet and physical activity to a standard non-drug insomnia therapy (CBT-I) could improve sleep quality. It involved 5 adults with chronic insomnia. Researchers measured changes in participants' sleep…

This study compared two numbing medicines used during breast reduction surgery to see which provides better pain relief afterward. Researchers tested a newer, longer-lasting numbing medicine against a standard one in 32 adult women. They measured patients' pain levels and opioid …

This study tested whether a special conversation guide, built into the patient's electronic medical record, could help people manage pain better after surgery. It aimed to see if this tool led to less pain, better physical function, and less use of opioid painkillers three months…

This study compared whether taking methadone as a pill before surgery works as well as getting it through an IV drip during surgery for managing pain after heart operations. It involved 41 patients having scheduled heart surgery. Researchers measured pain levels and how much addi…

This early study tested whether a cream containing ketoconazole could reduce the severity of a skin rash caused by a common class of cancer drugs (EGFR inhibitors). 58 patients with cancer who developed this rash were randomly assigned to use either the ketoconazole cream or a pl…

This study tested whether a 12-week virtual exercise program could help improve strength, balance, and quality of life for cancer survivors living in rural areas. The program involved 100 participants who had finished their main cancer treatments and used online sessions and acti…

This study tested a new wellness coaching program designed to support people caring for loved ones with advanced lung cancer. It compared standard support materials to the new coaching sessions to see which better helped caregivers manage stress and burden. The goal was to improv…

This small study aimed to understand if common detergents, like those in toothpaste, could damage the lining of the food pipe and trigger inflammation. Researchers tested this idea on 12 healthy volunteers by measuring changes in the esophagus after exposure. The goal was to gath…

This study aimed to understand exactly how strength training improves the body's ability to use insulin and builds muscle in older adults with insulin resistance, a condition that often leads to type 2 diabetes. Researchers compared 58 adults, some who did supervised strength tra…

This study examined how different levels of muscle relaxation affect the ease of placing a breathing tube during surgery. Researchers observed 170 patients undergoing elective surgery to determine the optimal timing for this procedure. The goal was to improve patient safety and c…

This study aimed to understand why some babies are born prematurely after undergoing surgery in the womb to treat birth defects like spina bifida. Researchers examined blood from 21 mothers and their partners, and placental tissue from babies, to see if the surgery triggers the m…

This study looked at how the way blood samples are collected, stored, and processed can affect the accuracy of tests that look for tiny pieces of cancer DNA in the blood. Researchers at Mayo Clinic worked with 114 women who had early-stage breast cancer to see if factors like the…

This study tested whether using a fitness tracker could help Black men who have had prostate cancer become more active and improve their quality of life. Thirteen participants wore the tracker for six weeks and had weekly check-ins. The main goal was to see if this approach was p…

This study tested whether a simple saliva sample, collected at home, could be used to track cytomegalovirus (CMV) infection in people being treated for ovarian cancer. Researchers compared virus levels in saliva to standard blood tests in 49 participants. The goal was to see if r…

This small Mayo Clinic study aimed to understand how specific immune cells called eosinophils interact with body fat in people with obesity and insulin resistance. Researchers enrolled 4 participants who were undergoing a weight-loss procedure to collect fat tissue and blood samp…

This study collected health information from breast cancer survivors to create a detailed research database. Researchers gathered blood, urine, saliva, and stool samples from 105 survivors who had finished active treatment. The goal is to use this data to better understand surviv…

This study aimed to see if a special health assessment for older adults could help predict who might experience more side effects from chemotherapy for multiple myeloma. Researchers followed 56 patients aged 65 and older, using questionnaires, tests, and blood samples to measure …

This study aimed to discover if certain inherited genes make people more likely to develop Primary Biliary Cirrhosis (PBC), a progressive liver disease. Researchers enrolled 1,500 people, including those with PBC and their close family members, to collect genetic information. The…

This study aimed to understand why some breast cancers are destroyed by standard chemotherapy while others are not. Researchers analyzed tumor samples and genetic information from 140 patients with invasive breast cancer who were receiving standard pre-surgery chemotherapy. The g…

This study aimed to understand how younger Black and Hispanic women perceive their personal risk of developing breast cancer. Researchers surveyed and interviewed 324 women without a history of breast cancer to learn how they think about risk and if it influences their health cho…

This study aimed to understand how a heart failure drug called Entresto (ARNI/LCZ 696) affects the body's kidney and hormone responses to a saltwater fluid challenge. It involved 72 people with type 2 diabetes, some with and some without very early signs of heart stiffness. The m…

This study aimed to understand why headaches continue for some people after a mild head injury and to find ways to predict and prevent them. Researchers followed 101 adults with recent post-traumatic headaches, tracking their symptoms, pain sensitivity, brain scans, and blood mar…

This study aimed to find out if a person's voice and speech change when they are experiencing a manic episode from bipolar disorder. Researchers recorded and analyzed the speech of 17 hospitalized patients during mania, looking at things like pitch, rhythm, sentence structure, an…

This study aimed to check how reliable certain lab tests are for measuring immune cells in people who have had or will have a kidney transplant. Researchers took two small bone marrow samples from 288 donors and recipients to see if the test results were consistent. The goal was …

This study tested whether wearable devices and smartphone apps could help monitor cancer patients' health from home. Researchers wanted to see if continuous remote tracking of vital signs and symptoms was more effective than standard check-ups only at the doctor's office. The stu…

This study tested whether a special type of PET/CT scan could help doctors see how well treatment is working for a rare salivary gland cancer that has spread. Six patients with this advanced cancer received the scan before and during their treatment. The goal was to see if change…

This study aimed to learn more about a harmful protein called tau in the brains of people with primary progressive aphasia (PPA) and frontotemporal dementia (FTD). Researchers used a special PET brain scan on 81 participants to see where and how much tau builds up in different ty…

This study aimed to find out if brain tumor (glioma) patients receiving oral chemotherapy at home were as satisfied with remote video visits (telehealth) as with traditional in-person clinic visits. It involved 30 patients who alternated between telehealth and in-person check-ups…

This study aimed to create a decision-making tool to help patients and doctors discuss treatment options after lung cancer surgery. Researchers observed conversations between 37 lung cancer patients and their doctors to understand how treatment decisions are made. The goal was to…

This study aimed to understand how women recover in the first three months after a scheduled cesarean delivery. Researchers followed 66 women, tracking their pain levels, use of pain medication, ability to perform daily activities, and emotional well-being. The goal was to create…

This study aimed to understand why people with obesity have different types of muscle fibers compared to lean individuals. Researchers compared 48 participants with and without obesity, using exercise and amino acid infusions to see how muscle proteins are made. The goal was to u…

This study aimed to find out if measuring a specific enzyme in the blood (called serum mast cell tryptase) could help predict which patients might develop painful stiffness after a total knee replacement. Researchers followed 219 patients with knee osteoarthritis before and after…

Researchers at Mayo Clinic tested a new type of wearable headset that aims to help people hear by sending sound signals through electrodes placed on the skin. The study involved 68 healthy volunteers to figure out the best settings for the device and to see how well people could …

This study aimed to check how accurately a special research treadmill can deliver controlled pushes or disturbances to a person's balance. Researchers at Mayo Clinic tested the treadmill on 12 healthy adults to see if the machine's movements matched what was commanded. The goal w…

This study aimed to understand if menopause affects heart muscle stiffness and exercise capacity in lifelong female endurance athletes. Researchers compared postmenopausal female athletes to premenopausal female athletes and similarly aged male athletes. They used special heart s…

This study looked at why some patients and their care teams successfully use non-drug pain management methods after surgery while others don't. Researchers analyzed 372 patients and their medical teams who were part of a larger pain management program. They wanted to understand w…

This study tested a new device called SimPull to see if it's a better way to move patients from one bed to another. Researchers compared it to current methods to see if it was faster, required fewer staff, and was safer for both patients and healthcare workers. The goal was to ga…