New brain scan could sharpen surgery for glioma patients

NCT ID NCT01165632

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study tested whether a special PET scan using 18F-FDOPA can help doctors better plan surgery and radiation for people with newly diagnosed brain tumors (gliomas). Twenty-four adults took part at Mayo Clinic. The goal was to see if the scan provides useful information beyond standard MRI, not to treat the tumor itself.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-FDOPA (a radioactive tracer used in PET scans)

What this could lead to

If successful, this could improve how doctors plan surgery and radiation for brain tumors, potentially leading to more precise treatment.

What could go wrong

This is a very early pilot study with only 24 participants. It is designed to gather information, not to test a treatment. The results may not change current practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adult anaplastic ependymoma adult astrocytic tumor adult brain ependymoma adult brainstem glioma adult glioblastoma adult oligodendroglioma anaplastic astrocytoma anaplastic oligodendroglioma astrocytoma (excluding glioblastoma) diffuse astrocytoma ependymoma giant cell glioblastoma glioblastoma glioma gliosarcoma low grade glioma malignant glioma mixed glioma myxopapillary ependymoma oligodendroglioma pilocytic astrocytoma pineal gland astrocytoma subependymal giant cell astrocytoma subependymoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States