New combo shows promise for Hard-to-Treat prostate cancer

NCT ID NCT05730712

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 28 times

Summary

This study tested a combination of two targeted drugs (pertuzumab and trastuzumab) plus a chemotherapy drug (enzalutamide) in 7 men with advanced prostate cancer that had spread and stopped responding to standard hormone treatments. The goal was to see if this mix could shrink tumors or slow the cancer's growth. The approach uses antibodies to block cancer growth signals and chemotherapy to kill cancer cells.

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Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.