Precision radiation may tame rising PSA after prostate surgery
NCT ID NCT04915508
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This phase II trial tests a highly precise, short-course radiation therapy (SBRT) combined with hormone therapy for men whose PSA levels rise after prostate cancer surgery. The goal is to control the cancer while reducing side effects by delivering higher radiation doses in fewer sessions. The study measures quality of life and symptom changes in participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Stereotactic Body Radiation Therapy (SBRT) and hormone therapy
- What this could lead to
- If successful, this approach could offer a shorter, more precise radiation course with fewer side effects for men with rising PSA after prostatectomy.
- What could go wrong
- This is a mid-stage trial, so the approach may not prove effective or safe for all patients. Side effects from radiation and hormone therapy are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095, United States
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- Hormone therapy plus precision radiation aims to crush prostate cancer early