New PET scan could spot liver cancer spread more clearly

NCT ID NCT05176223

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tested whether a special PET scan using a radioactive tracer called 68Ga-PSMA can better detect advanced liver cancer that has spread. The tracer attaches to a protein found on liver cancer cells, making them visible on the scan. The study involved 29 adults with advanced liver cancer who were eligible for standard immunotherapy. The goal was to see if this imaging method improves diagnosis and helps guide treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Gallium Ga 68 Gozetotide (68Ga-PSMA)

What this could lead to

If successful, this imaging method could help doctors better detect and manage advanced liver cancer, potentially leading to more personalized treatment.

What could go wrong

This was a small, early-phase trial with only 29 participants. The imaging technique may not prove significantly better than standard methods, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States