Triple attack on lymphoma: freeze, vaccinate, and boost immunity

This study tested a new combination treatment for people with non-Hodgkin lymphoma that had come back. The approach used three steps: first, freezing the tumor to kill cancer cells; second, injecting a personalized vaccine made from the patient's own immune cells; and third, giving an immunotherapy drug (pembrolizumab) to help the immune system attack the cancer. The goal was to find the safest dose and see if the treatment could shrink tumors. Eleven adults took part in this early-phase trial.