Proton beam doses put to the test for tough lung cancers
NCT ID NCT03132532
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tested different doses of proton beam therapy combined with standard chemotherapy for people with stage 2-3 non-small cell lung cancer that cannot be surgically removed. The goal was to find the best radiation dose to control the cancer. Twenty participants received treatment, and researchers tracked how long the cancer stayed under control and overall survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- proton beam therapy and platinum doublet chemotherapy (carboplatin, cisplatin, paclitaxel, etoposide, pemetrexed)
- What this could lead to
- If successful, this could help determine the best proton beam dose to improve outcomes for people with inoperable lung cancer.
- What could go wrong
- This is a small, early-phase trial with only 20 participants, so results may not apply to everyone. The optimal dose may not clearly improve survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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