STAGE II LUNG CANCER AJCC V8

This study is testing whether updating radiation treatment plans at set times during therapy can reduce damage to healthy heart and lung tissue in people with non-small cell lung cancer. Researchers want to see if this adaptive approach lowers side effects like lung inflammation …

This study is for people with early-stage non-small cell lung cancer who have had surgery and whose initial treatment completely removed the cancer. It compares two approaches: one group receives a year of immunotherapy (durvalumab) to try to prevent the cancer from returning, wh…

This study is testing whether giving two immunotherapy drugs before surgery can help the body's immune system attack and shrink early-stage non-small cell lung cancer. The goal is to kill more cancer cells before the tumor is removed, potentially leading to better long-term resul…

This large, late-stage trial is testing if adding an immunotherapy drug (pembrolizumab) to standard chemotherapy helps patients live longer without their cancer returning. It is for people with stage II or III non-small cell lung cancer who have already had their tumor surgically…

This study is testing whether artificial intelligence (AI) software can help doctors determine the best radiation dose for each patient's lung tumor. It aims to see if this personalized approach can better control the cancer and reduce side effects compared to standard dosing. Ab…

This large study aims to find the best timing for cancer treatments in people with operable non-small cell lung cancer. It will compare the standard approach of giving chemotherapy and immunotherapy only after surgery to a newer approach of giving it both before and after surgery…

This study is testing if a drug called canakinumab can prevent lung cancer in people who have suspicious, high-risk spots (nodules) in their lungs. About 50 participants will receive injections of the drug every 3 weeks for up to 8 cycles. The main goal is to see if the drug can …

This study is testing whether a special breathing exercise program before lung cancer surgery can help prevent serious lung problems like pneumonia after the operation. It involves 220 patients with early to mid-stage lung cancer. Half will do breathing muscle training with a dev…

This study is testing whether a yoga program for patients and their caregivers can improve physical function and quality of life during radiation treatment for lung or esophageal cancer. It will compare yoga sessions to educational sessions to see which helps patients walk farthe…

This study is testing whether a home-based breathing exercise program can help people who have had early-stage lung cancer. Many survivors experience shortness of breath and fatigue after treatment, which makes it hard to stay active. Researchers want to see if strengthening brea…

This study is testing whether a special communication tool helps doctors and patients with non-small cell lung cancer make treatment decisions together more effectively. The tool guides conversations about treatment options, benefits, and risks while considering each patient's pe…

This study aims to see if providing patients with quality-of-life information helps them make better decisions about their early-stage lung cancer treatment. It compares two groups: one receives a fact sheet about life after surgery or radiation, and the other receives standard c…

This study aims to understand if the order a surgeon cuts the blood vessels during lung cancer surgery affects how much cancer DNA is left in the bloodstream afterward. Researchers will compare two standard techniques—cutting the vein first versus cutting the artery first—in 100 …

This study aims to understand why some cancer patients develop severe diarrhea and colon inflammation (colitis) while taking powerful immunotherapy drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 patients with melanoma…