STAGE II LUNG CANCER AJCC V8

This study tests whether adding an immunotherapy drug (atezolizumab) to standard radiation therapy helps people with early-stage non-small cell lung cancer live longer. About 480 participants with stage I-IIA lung cancer will receive either radiation alone or radiation plus atezo…

This early-phase study tests a drug called NBTXR3, which makes cancer cells more sensitive to radiation, combined with a second round of radiation for people whose non-small cell lung cancer has returned and cannot be removed by surgery. The main goals are to find the safest dose…

This study tests whether adding a drug called AZD6738 to the immunotherapy durvalumab can help keep lung cancer from returning in patients who have already had chemotherapy and surgery. About 630 adults with stage II to IIIB non-small cell lung cancer will take part. The goal is …

This study compares two treatments for lung lesions in people with non-small cell lung cancer, sarcoma, or colorectal cancer that has spread. One treatment uses microwave energy to heat and kill tumor cells, while the other is a small surgery to remove the tumor. Researchers want…

This study is for people with stage II or III non-small cell lung cancer who are not healthy enough for standard treatments. It tests a shorter, stronger course of radiation followed by the immunotherapy drug atezolizumab. The goal is to see if this combination is safe and helps …

This early-phase trial tests whether combining two immunotherapy drugs (ipilimumab and nivolumab) with radiation therapy is safe and effective for people with stage II or III non-small cell lung cancer that cannot be removed by surgery. The study includes 21 participants and aims…

This study tests whether adding the immunotherapy drug atezolizumab to standard chemoradiation helps people with limited stage small cell lung cancer live longer. About 544 participants receive either chemoradiation alone or chemoradiation plus atezolizumab. The goal is to see if…

This study tests whether a lung cancer drug called atezolizumab can be safely given at home by a nurse, with doctor visits done by video call. It involves 5 adults with non-small cell lung cancer. The goal is to see if this home-based approach is practical and safe.

This study tests an online program designed to improve social well-being and emotional support for women with non-small cell lung cancer. About 70 women currently receiving treatment will use mindfulness and compassion techniques to help manage distress. The goal is to see if the…

This study tests a telehealth self-management program for people who have finished treatment for early-stage lung or colorectal cancer. The program coaches survivors on follow-up care, communication with doctors, and managing their health. Researchers want to see if it improves c…

This study follows over 1,300 people with breast, lung, or ovarian cancer who are starting a type of chemotherapy called taxane. The goal is to find out which patients are more likely to develop nerve damage (peripheral neuropathy), which can cause tingling or numbness in the han…

This study tests a conversation aid designed to help people with lung cancer and their doctors make treatment decisions together. About 98 patients will use the tool to see if it reduces anxiety and regret while improving understanding. The goal is to make decision-making easier …