Can a common fungal drug soothe cancer treatment rash?

NCT ID NCT03471364

Completed Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times

Summary

This study tested whether ketoconazole, a drug usually used for fungal infections, can help reduce skin rashes caused by EGFR inhibitor cancer therapy. 58 participants with ongoing rash were randomly assigned to receive ketoconazole or a placebo. The main goal was to see if the drug improved rash symptoms over 4 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle on Vermilion

Danville, Illinois, 61832, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
Park Nicollet Frauenshuh Cancer Center

Saint Louis Park, Minnesota, 55426, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
University of Rochester

Rochester, New York, 14642, United States

Conditions

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MALIGNANT NEOPLASM