Could a Sugar-Water injection ease knee arthritis?
NCT ID NCT05160532
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests whether injecting a concentrated sugar-water solution (dextrose) into the knee joint can reduce pain and improve function in people with knee osteoarthritis. Participants receive either the dextrose injection or a placebo (salt-water injection) under ultrasound guidance. The goal is to find the best injection schedule and see if this simple, low-cost approach provides meaningful relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dextrose (sugar water)
- What this could lead to
- If it works, this could offer a simple, low-cost injection treatment to reduce knee pain and improve mobility without surgery.
- What could go wrong
- This is a small, early-phase study, so results may not apply to everyone. The injection may cause temporary pain or swelling, and it is unclear if it works better than a placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Arizona
Scottsdale, Arizona, 85260, United States
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