New PET/MR scan could spot nerve amyloid without a biopsy
NCT ID NCT03019029
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study tested whether a special PET/MR scan using a radioactive tracer called F-18 florbetapir can detect amyloid protein buildup in the nerves of people with amyloidosis. Eight adults with confirmed nerve amyloidosis or other nerve diseases took part. The goal was to see if the scan could tell the difference between amyloid and non-amyloid nerve problems.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
18-F Florbetapir (a radioactive tracer used in PET scans)
What this could lead to
If successful, this scan could become a new way to diagnose nerve amyloidosis without needing a biopsy.
What could go wrong
This was a very small, early-phase study with only 8 participants. The results may not apply to everyone, and the scan is not yet a standard test.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.