Scientists investigate the roots of persistent Post-Concussion headaches

NCT ID NCT04369729

Completed Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed study looked at 101 adults who developed headaches within 7 to 56 days after a mild head injury. Researchers used brain scans, blood tests, and pain sensitivity tests to find clues about who might develop long-term headaches. The goal was to better understand the mechanisms behind persistent post-traumatic headache, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward ways to predict and prevent long-term headaches after a mild head injury.
What could go wrong: This is an observational study, not a treatment trial. It aims to understand the problem, not test a cure or therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POST TRAUMATIC HEADACHE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Post-Traumatic Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST TRAUMATIC HEADACHE

Contacts and locations

Locations

Mayo Clinic

Phoenix, Arizona, 85054, United States
Mayo Clinic

Scottsdale, Arizona, 85259, United States
Mayo Clinic

Jacksonville, Florida, 32224, United States
Mayo Clinic

Rochester, Minnesota, 55901, United States
Phoenix VA Health Care System

Phoenix, Arizona, 85012, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.