Could your toothpaste be harming your esophagus?

NCT ID NCT05482256

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether detergents found in common products like toothpaste can make the lining of the esophagus leaky and cause allergic inflammation, which is a key feature of eosinophilic esophagitis. Researchers tested 12 healthy volunteers by measuring changes in the esophagus after exposure to detergents. The goal was to understand a possible cause of this condition, not to test a treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic Arizona

    Scottsdale, Arizona, 85259, United States

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