EOSINOPHILIC ESOPHAGITIS

This study is testing whether a daily pill called vonoprazan can help adults with eosinophilic esophagitis (EoE), a condition that causes painful swallowing and inflammation in the food pipe. Researchers will compare the pill to a placebo (inactive pill) over 12 weeks to see if i…

This small pilot study is testing whether a common acid reflux medication (proton pump inhibitor or PPI) can improve the flexibility of the esophagus in adults with eosinophilic esophagitis (EoE). Researchers will measure how stretchy the upper and lower parts of the esophagus ar…

This study is testing an experimental drug called EP-104GI for adults with eosinophilic esophagitis (EoE), a condition that causes painful swallowing and inflammation in the food pipe. The drug is a long-acting steroid injected directly into the esophagus during a standard scope …

This study is testing whether a medication called Zemaira, given as a weekly infusion for four weeks, can help adults with eosinophilic esophagitis. Researchers want to see if the treatment reduces inflammation in the esophagus and improves symptoms. The study will also monitor f…

This study aims to learn how well the medication dupilumab works for people with eosinophilic esophagitis (EoE) in everyday life over two years. It will follow 150 patients in Germany who are already starting this treatment to see how it affects their symptoms, safety, and qualit…

This study is testing whether taking 1mg of budesonide tablets twice daily works as well as taking 2mg once daily for treating eosinophilic esophagitis (EoE). Researchers will enroll 308 adults with active EoE to compare how effectively each dosing schedule reduces inflammation a…

This study is testing a new, simpler way to diagnose eosinophilic esophagitis (EoE), a condition that causes painful swallowing. Researchers want to see if a swallowable string that collects fluid from the throat is as accurate as the current standard test, which requires a more …

This study is testing a new, FDA-approved device called Mivu that measures the lining of the food pipe (esophagus) during a routine endoscopy. The goal is to see if this quick, one-step test can accurately diagnose conditions like GERD (chronic acid reflux) and eosinophilic esoph…

This is an observational study aiming to understand why food allergies develop and how they progress over time. Researchers will follow up to 1,800 participants, including people with food allergies, their relatives, and healthy volunteers, for many years. The study involves coll…

This study aims to understand how common immediate food reactions are in children with eosinophilic esophagitis (EoE). Researchers will observe 40 children aged 6-18 who experience throat pain, pressure, or choking within minutes of eating certain foods. The goal is to gather inf…

This study aims to find easier, noninvasive ways to monitor eosinophilic esophagitis (EoE), a chronic allergic/immune condition that causes swallowing problems in children. Currently, tracking the disease requires repeated endoscopies under anesthesia. Researchers will check if s…

This study aims to build a large database and sample collection to learn more about a group of rare digestive diseases called eosinophilic gastrointestinal disorders (EGIDs). Researchers will collect information from up to 500 patients about their symptoms, quality of life, and t…

This study aims to find better ways to measure how patients with eosinophilic gastrointestinal disorders (EGIDs) are doing. It will follow 1350 children and adults over time during their normal doctor visits. Researchers will compare tissue samples from routine scopes with answer…