Scientists seek better yardsticks for rare gut diseases

NCT ID NCT02523118

Recruiting now Knowledge-focused Sponsor: Children's Hospital Medical Center, Cincinnati Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is looking at people with eosinophilic gastrointestinal disorders, which cause inflammation in the gut. Researchers want to see if simple questionnaires can tell how well a patient is doing, compared to looking at tissue samples from endoscopies. The goal is to find better ways to measure disease activity and guide treatment. The study will include 1,350 children and adults.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand and monitor eosinophilic disorders, leading to improved treatment decisions.
What could go wrong: This is an observational study, not testing a new treatment. It may not directly change patient care, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

eosinophilic colitis Eosinophilic enteropathy eosinophilic esophagitis eosinophilic gastritis eosinophilic gastroenteritis eosinophilic gastrointestinal disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EOSINOPHILIC COLITIS EOSINOPHILIC ESOPHAGITIS EOSINOPHILIC GASTRITIS EOSINOPHILIC GASTROENTERITIS EOSINOPHILIC GASTROINTESTINAL DISORDERS (EGIDS)

Contacts and locations

Locations

Ann and Robert H. Lurie Children's Hospital of Chicago
RECRUITING

Chicago, Illinois, 60611, United States
Arkansas Children's Research Institute
RECRUITING

Rogers, Arkansas, 72758, United States
Baylor College of Medicine & Texas Children's Hospital
RECRUITING

Houston, Texas, 77030, United States
Children's Hospital Colorado
RECRUITING

Denver, Colorado, 80218, United States
Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Cincinnati Children's Hospital Medical Center
RECRUITING

Cincinnati, Ohio, 45229, United States
Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States
Mayo Clinic
COMPLETED

Rochester, Minnesota, 55902, United States
Mayo Clinic Hospital
RECRUITING

Phoenix, Arizona, 85054, United States
National Institutes of Health (NIH)
RECRUITING

Bethesda, Maryland, 20892, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60208, United States
Rady Children's Hospital
RECRUITING

San Diego, California, 92123, United States
Riley Children's Hospital
COMPLETED

Indianapolis, Indiana, 46202, United States
Tufts University
COMPLETED

Boston, Massachusetts, 02111, United States
University of Colorado Denver
RECRUITING

Aurora, Colorado, 80045, United States
University of North Carolina, Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27599, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Utah
RECRUITING

Salt Lake City, Utah, 84112, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States

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