Swallowable sponge could replace endoscopy for esophagitis monitoring
NCT ID NCT06501274
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This study tests a capsule sponge device as a less invasive alternative to endoscopy for checking how well treatment is working in people with eosinophilic esophagitis (a chronic allergic condition of the esophagus). Participants swallow a capsule attached to a string, which expands into a sponge to collect cell samples. The trial will compare the sponge's results with symptom questionnaires and see if it changes treatment decisions. It also measures patient pain and preference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- capsule sponge
- What this could lead to
- If successful, this could offer a simpler, less invasive way to monitor treatment response in eosinophilic esophagitis, reducing the need for repeated endoscopies.
- What could go wrong
- This is a small, single-site study. The capsule sponge may not provide enough tissue for analysis, and some patients may not be able to swallow it. It is not a treatment, only a monitoring tool.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
East and North Herts NHS Trust
Stevenage, Hertfordshire, SG1 4AB, United Kingdom
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